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子宫内膜癌生育力保存治疗后经体外受精和胚胎移植连续两次活产的病例报告

A Case Report of Consecutive Live Birth Twice Through in vitro Fertilization and Embryo Transfer After Endometrial Carcinoma Fertility Preservation Treatment.

作者信息

Wang Jingying, Fang Ying, Chen Tong, Xin Zhimin, Wu Yumei, Yang Xiaokui

机构信息

Department of Human Reproductive Medicine, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, People's Republic of China.

Department of Human Reproductive Medicine, Beijing Maternal and Child Health Care Hospital, Beijing, People's Republic of China.

出版信息

Int J Womens Health. 2024 Mar 6;16:395-400. doi: 10.2147/IJWH.S441984. eCollection 2024.

Abstract

Preserving fertility is a vital concern for young women diagnosed with endometrial carcinoma. The clinical management of such patients is often disappointing. It is rare to have two consecutive successful pregnancies. We present a child-bearing-age woman who underwent fertility preservation therapy due to endometrial carcinoma. Following fertility preservation therapy, she underwent in vitro fertilization and embryo transfer. After receiving her first fresh embryo transfer, she successfully conceived and gave birth to a healthy child. Two years after the first embryo transfer and regular follow-up, she had another frozen embryo transfer of two cleavage embryos and successfully gave birth to another healthy baby. After the delivery of her second child, she underwent surgical treatment for endometrial carcinoma. For endometrial carcinoma patients who intend to preserve fertility, high-quality long-term follow-up and personalized treatment are necessary.

摘要

对于被诊断为子宫内膜癌的年轻女性来说,保留生育能力是一个至关重要的问题。这类患者的临床治疗往往不尽人意。连续两次成功怀孕的情况很少见。我们介绍一位因子宫内膜癌接受生育力保留治疗的育龄妇女。在接受生育力保留治疗后,她接受了体外受精和胚胎移植。在接受首次新鲜胚胎移植后,她成功受孕并生下一个健康的孩子。在首次胚胎移植并定期随访两年后,她又进行了一次两个卵裂期胚胎的冻融胚胎移植,并成功生下另一个健康的婴儿。在生下第二个孩子后,她接受了子宫内膜癌的手术治疗。对于打算保留生育能力的子宫内膜癌患者,高质量的长期随访和个性化治疗是必要的。

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