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术前评估过程对接受减肥与代谢手术患者体重减轻及血糖控制的影响。

The impact of a preoperative evaluation process on weight reduction and glycemic control in patients undergoing bariatric and metabolic surgery.

作者信息

Tempany Jennifer, Collier Andrew, Ali Abdulmajid

机构信息

Bariatric Surgery Unit University Hospital Ayr Ayr UK.

School of Health & Life Sciences Glasgow Caledonian University Glasgow UK.

出版信息

Obes Sci Pract. 2024 Mar 8;10(2):e735. doi: 10.1002/osp4.735. eCollection 2024 Apr.

Abstract

INTRODUCTION

Metabolic surgery is a sustainable intervention for obesity and type 2 diabetes. Preoperative education optimizes weight loss and glycemic control outcomes.

OBJECTIVE

This study aimed to determine the effect of a generalized preoperative evaluation process (PEP) in patients who underwent bariatric surgery on weight loss and glycemic control pre- and post-surgery.

METHODS

Data were retrospectively collected and analyzed for patients with type 2 diabetes who underwent bariatric surgery between 2010 and 2016. Patients were categorized into two groups determined by participation in the PEP. The groups were named the PEP group and non-PEP group. The correlation among engagement in the PEP was determined using the chi-square test and -test. Statistical analysis with  < 0.05 was deemed significant.

RESULTS

129 patients were included in the study; 86 females (67%) and 43 males (33%). Fifty-nine patients (46%) engaged in the PEP and 70 (54%) patients did not engage in the PEP. A greater reduction in weight loss was observed in the PEP group versus the non-PEP group from initial enrollment to pre-surgery (14.3 ± 9.2 kg vs. 11.6 ± 9.2 kg;  = 0.11), and from pre-surgery to 2-years post-surgery (20.6 ± 14.8 kg vs. 16.9 ± 15.6 kg;  = 0.17). A greater reduction in HbA1c from initial enrollment to pre-surgery was seen in the PEP group versus the non-PEP group (0.90 ± 1.28% vs. 0.63 ± 1.07%); however, this was not maintained from pre-surgery to 2-year post-surgery (0.51 ± 1.18% vs. 0.70 ± 1.73%). In both cases, the statistical difference was insignificant.

CONCLUSION

The PEP was not associated with improvements in short-term weight loss or glycemic control pre-surgery and a 2-years post-surgery. Patients may benefit from individually tailored preoperative weight management strategies.

摘要

引言

代谢手术是治疗肥胖症和2型糖尿病的一种可持续干预措施。术前教育可优化体重减轻和血糖控制效果。

目的

本研究旨在确定全面术前评估流程(PEP)对接受减肥手术患者术前及术后体重减轻和血糖控制的影响。

方法

回顾性收集并分析2010年至2016年间接受减肥手术的2型糖尿病患者的数据。根据是否参与PEP将患者分为两组。这两组分别命名为PEP组和非PEP组。使用卡方检验和t检验确定参与PEP之间的相关性。P<0.05的统计分析被认为具有显著性。

结果

129例患者纳入研究;86例女性(67%)和43例男性(33%)。59例患者(46%)参与了PEP,70例(54%)患者未参与PEP。从初始入组到术前,PEP组比非PEP组体重减轻幅度更大(14.3±9.2千克对11.6±9.2千克;P = 0.11),从术前到术后2年也是如此(20.6±14.8千克对16.9±15.6千克;P = 0.17)。从初始入组到术前,PEP组的糖化血红蛋白降低幅度大于非PEP组(0.90±1.28%对0.63±1.07%);然而,从术前到术后2年这一差异未持续存在(0.51±1.18%对0.70±1.73%)。在这两种情况下,统计学差异均不显著。

结论

PEP与术前及术后2年的短期体重减轻或血糖控制改善无关。患者可能受益于个性化定制的术前体重管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c686/10924108/1b2bbac08173/OSP4-10-e735-g002.jpg

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