Department of Pediatrics, 37977 Ajou University School of Medicine , Suwon, Korea.
J Pediatr Endocrinol Metab. 2024 Mar 12;37(5):472-476. doi: 10.1515/jpem-2023-0538. Print 2024 May 27.
Lingual thyroid is a rare condition that affects approximately 1 in 100,000 individuals. Although it is usually detected in the pediatric population through newborn screening tests or evaluation of congenital hypothyroidism, there are cases in which it remains undetected until adulthood or until symptoms arise because of glandular enlargement. The possible symptoms of lingual thyroid include foreign body sensation in the throat, dysphagia, dyspnea, and hemorrhage. Several cases of lingual thyroid are asymptomatic and accompanied by subclinical hypothyroidism. Herein, we present three cases of lingual thyroid treated with thyroid hormone suppressive therapy.
The three patients sought medical attention because of a sore throat or foreign body sensation in the throat. Their newborn screening tests and developmental histories were normal. These patients exhibited subclinical hypothyroidism and were treated with hormone suppression therapy.
Patients with lingual thyroid frequently exhibit subclinical hypothyroidism. Hormone treatment may help to reduce the size of the ectopic thyroid and improve symptoms. If an increase in size is noted during follow-up or symptoms do not improve, surgical treatments may be considered.
舌甲状腺是一种罕见的疾病，影响大约每 10 万人中有 1 人。尽管它通常通过新生儿筛查测试或评估先天性甲状腺功能减退症在儿科人群中被发现，但也有一些病例直到成年或由于腺体肿大出现症状才被发现。舌甲状腺的可能症状包括喉咙异物感、吞咽困难、呼吸困难和出血。一些无症状的舌甲状腺病例伴有亚临床甲状腺功能减退症。在此，我们介绍了 3 例经甲状腺激素抑制治疗的舌甲状腺病例。
这 3 位患者因喉咙痛或喉咙异物感而就医。他们的新生儿筛查测试和发育史均正常。这些患者表现为亚临床甲状腺功能减退症，并接受了激素抑制治疗。
舌甲状腺患者常伴有亚临床甲状腺功能减退症。激素治疗可能有助于缩小异位甲状腺的大小并改善症状。如果在随访过程中发现增大或症状未改善，可考虑手术治疗。
