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主动脉瓣纤维弹性瘤伴非阻塞性冠状动脉心肌梗死(MINOCA):一例病例报告及文献综述

Aortic valve fibroelastoma presenting with myocardial infarction with non-obstructive coronary arteries (MINOCA): A case report and review of the literature.

作者信息

Pepe Martino, Tritto Rocco, Naccarati Maria Ludovica, Quarta Simona, Marzullo Andrea, Ciccone Marco Matteo

机构信息

Cardiovascular Diseases Section, Interdisciplinary Department of Medicine (DIM), University of Bari "Aldo Moro", 70124 Bari, Italy.

Cardiovascular Diseases Section, Interdisciplinary Department of Medicine (DIM), University of Bari "Aldo Moro", 70124 Bari, Italy.

出版信息

Cardiovasc Pathol. 2024 Jul-Aug;71:107631. doi: 10.1016/j.carpath.2024.107631. Epub 2024 Mar 10.

Abstract

Cardiac papillary fibroelastomas (CPFs) are rare benign cardiac tumors more often involving the left-sided valves and related with threatening embolic complications. We report the case of a 35-year-old woman presenting with relapsing-remitting chest pain and elevated cardiac troponins. After a negative coronary angiography, an integrated imaging assessment based on echocardiography and cardiac magnetic resonance showed a pedunculated mass on the aortic valve causing an intermittent obstructive engagement of the right coronary ostium. A tailored surgical treatment was performed and the histopathological examination of the specimen revealed mesenchymal tissue with the characteristics of CPF.

摘要

心脏乳头肌纤维弹性瘤(CPFs)是一种罕见的心脏良性肿瘤,更常累及左侧瓣膜,并与威胁生命的栓塞并发症相关。我们报告了一例35岁女性患者,该患者反复出现胸痛且心肌肌钙蛋白升高。冠状动脉造影结果为阴性后,基于超声心动图和心脏磁共振成像的综合影像评估显示主动脉瓣上有一个带蒂肿块,导致右冠状动脉开口间歇性阻塞。实施了针对性的手术治疗,标本的组织病理学检查显示为具有CPF特征的间叶组织。

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