Zhang Dong-Liang, Zhang Wei, Ren Yi-Ming, Zhao Wen-Jun, Sun He-Jun, Tian Zheng-Wei, Tian Meng-Qiang
Department of Joint and Sport Medicine, Tianjin Union Medical Center, Tianjin Medical University, Nankai University Affiliated People's Hospital, Jieyuan Road 190, Hongqiao District, Tianjin, 300121, People's Republic of China.
Nursing Department, Tianjin Union Medical Center, Nankai University Affiliated People's Hospital, Tianjin, People's Republic of China.
Sci Rep. 2024 Mar 11;14(1):5882. doi: 10.1038/s41598-024-56300-1.
The presence of heterotopic ossification (HO) after primary total knee replacement (TKR) is rare and associated with limited mobility and stiffness of the knee. This study aimed to identify if the arthroscopic debridement after TKR could decrease HO and improve the function and range of motion. Thirty HO patients after TKR were retrospectively separated into 2 cohorts. 15 patients of group A accepted the arthroscopic debridement, while 15 patients of group B only had non-operative treatment, mainly including oral nonsteroidal anti-inflammatory drugs (NSAIDs) and rehabilitative treatment. Visual analog scale (VAS) scores, knee society knee scores (KSS), range of motion (knee flexion and knee extension) were obtained before treatment and at 1 month, 3 months, and 6 months after treatment. Radiography of after-treatment was also evaluated to assess the changes in HO. There were 3 males and 27 females with a mean age of 67.4 ± 0.8 years in group A and 68.2 ± 1.3 in group B. The onset time of HO was 3-6 months. The maximum size of the ossification was < 2 cm in 23 knees, 2 cm < heterotopic bone < 5 cm in 6 knees and > 5 cm in 1 knee. The size of HO decreased gradually in all knees by X-ray film at the last follow-up. There were no significant differences in VAS scores after replacement between two groups (p > 0.05). The average range of motion preoperatively in group A was - 15.2-90.6°, which postoperatively increased to - 4.2-110.0°. Meanwhile, the KSS scores and average range of motion of the group A were better than those of the group B at each follow-up time after treatment. Arthroscopic debridement can decrease HO seen from postoperative X-rays, improve the function and range of motion, as well as the pain remission between two groups are comparable. Consequently, arthroscopic resection of HO after TKR is recommended as soon as there is aggravating joint stiffness.
初次全膝关节置换术(TKR)后出现异位骨化(HO)的情况较为罕见,且与膝关节活动受限和僵硬有关。本研究旨在确定TKR术后关节镜下清创术是否能减少HO,并改善膝关节功能和活动范围。30例TKR术后发生HO的患者被回顾性分为2组。A组15例患者接受关节镜下清创术,而B组15例患者仅接受非手术治疗,主要包括口服非甾体抗炎药(NSAIDs)和康复治疗。在治疗前以及治疗后1个月、3个月和6个月时,获取视觉模拟量表(VAS)评分、膝关节协会膝关节评分(KSS)、活动范围(膝关节屈曲和伸展)。还对治疗后的X线片进行评估,以评估HO的变化情况。A组有3名男性和27名女性,平均年龄为67.4±0.8岁,B组平均年龄为68.2±1.3岁。HO的发病时间为3至6个月。23个膝关节的骨化最大尺寸<2 cm,6个膝关节的异位骨尺寸在2 cm至5 cm之间,1个膝关节的异位骨尺寸>5 cm。在最后一次随访时,通过X线片观察到所有膝关节的HO尺寸均逐渐减小。两组置换术后VAS评分无显著差异(p>0.0