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斯里兰卡中北部省份医院诊断的慢性肾脏病/慢性肾脏病不明原因型发病率下降：这与饮用水反渗透厂的供应有关吗？

Decreasing incidence of hospital diagnosed CKD/CKDu in North Central Province of Sri Lanka: is it related to provision of drinking water reverse osmosis plants?

作者信息

Ranasinghe Asanga Venura, Somatunga Lakshmi C, Kumara Gardiye Weligamage Gamini Priyantha, Karunarathna Ranamuka Henayage, De Silva Ambepitiyawaduge Pubudu, Gunawardena Jayaprakara Mudiyanselage Chathurika Nayani, Kumari Sembu Kuttige Champika Ruwan, Sarjana Mohamed Shali Fathima, De Silva Mannikawadumesthri Vipula Chandu

机构信息

National Renal Disease Prevention and Research Unit, Ministry of Health, Colombo 10, Sri Lanka.

Office of Additional Secretary, Ministry of Health, Colombo 10, Sri Lanka.

出版信息

BMC Nephrol. 2024 Mar 11;25(1):91. doi: 10.1186/s12882-024-03534-w.

DOI:10.1186/s12882-024-03534-w
PMID:38468233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10926649/
Abstract

BACKGROUND

We assessed the possible impact of provision of reverse osmosis (RO) water on the incidence of hospital diagnosed CKD/CKDu in North Central Province (NCP) of Sri Lanka.

METHODS

An ecological study was conducted on data from 2010-2020 on the incidence of hospital diagnosed CKD/CKDu, CKD/CKDu screening and provision of drinking water RO plants in NCP. Analysis was conducted using descriptive statistics, ANOVA and chi-square test.

RESULTS

The annual incidence of hospital diagnosed CKD/CKDu (per 100 000 population) in 2010-2013, 2014-2016 and 2017-2020 periods in Anuradhapura district were 129.07, 331.06 and 185.57 (p = 0.002) while in Polonnaruwa district these were 149.29, 326.12 and 296.73 (p = 0.04) respectively. In NCP provision of RO plants commenced after 2011 and the decline in the incidence of hospital diagnosed CKD/CKDu was seen in 25 of the 29 Divisional Secretary Divisions when more than 20% of the families received access to drinking RO water projects.

CONCLUSIONS

The annual incidence of hospital diagnosed CKD/CKDu increased in NCP from 2010 to 2016 and continuously decreased thereafter. Continuous declining of CKD/CKDu incidence was seen after more than 20% of the families received access to drinking water RO plants.

摘要

背景

我们评估了提供反渗透（RO）水对斯里兰卡中北部省（NCP）医院诊断的慢性肾脏病/慢性肾脏病-不明原因（CKD/CKDu）发病率的可能影响。

方法

对2010 - 2020年NCP医院诊断的CKD/CKDu发病率、CKD/CKDu筛查及饮用水RO工厂供应的数据进行了一项生态学研究。使用描述性统计、方差分析和卡方检验进行分析。

结果

2010 - 2013年、2014 - 2016年和2017 - 2020年期间阿努拉德普勒区医院诊断的CKD/CKDu年发病率（每10万人口）分别为129.07、331.06和185.57（p = 0.002），而波隆纳鲁沃区分别为149.29、326.12和296.73（p = 0.04）。在NCP，RO工厂的供应于2011年后开始，当超过20%的家庭能够使用饮用水RO水项目时，在29个分区秘书分区中的25个分区中，医院诊断的CKD/CKDu发病率出现了下降。

结论

2010年至2016年NCP医院诊断的CKD/CKDu年发病率上升，此后持续下降。在超过20%的家庭能够使用饮用水RO工厂后，CKD/CKDu发病率持续下降。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b515/10926649/6756f0f6c9cb/12882_2024_3534_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b515/10926649/17c5ea982878/12882_2024_3534_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b515/10926649/6778ac2d0810/12882_2024_3534_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b515/10926649/6756f0f6c9cb/12882_2024_3534_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b515/10926649/17c5ea982878/12882_2024_3534_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b515/10926649/6778ac2d0810/12882_2024_3534_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b515/10926649/6756f0f6c9cb/12882_2024_3534_Fig3_HTML.jpg

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Ann Nutr Metab. 2020;76 Suppl 1:37-42. doi: 10.1159/000515018. Epub 2021 Mar 26.
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Chronic kidney disease of non-traditional origin in Mesoamerica: a disease primarily driven by occupational heat stress.中美洲非传统病因所致的慢性肾病：一种主要由职业性热应激引发的疾病。
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