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白藜芦醇:阿尔茨海默病的保护剂。

Resveratrol: Protective Agent Against Alzheimer's Disease.

机构信息

Laboratory of Alternative Animal Models, Section of Genetics, Department of Zoology, Faculty of Life Science, Aligarh Muslim University, Aligarh, 202002, Uttar Pradesh, India.

出版信息

Cent Nerv Syst Agents Med Chem. 2024;24(3):249-263. doi: 10.2174/0118715249287167240222081517.

Abstract

Resveratrol is a biologically active natural phenolic plant product. It has several properties which make them useful to treat the disease. In this review, we have highlighted the neuroprotective effects of resveratrol. Several available animal models have been proven to help understand the disease pathway and mechanism of action by resveratrol. In this review, we have highlighted the neuroprotective activity of resveratrol in AD, which effectively counter the neurodegenerative disease by decreasing the formation of plaques. Resveratrol is a natural plant product that is easily available, cost-effective, and possesses neuroprotective activity, which is useful for treating neurodegenerative diseases. Resveratrol presents a promising avenue for AD treatment due to its diverse neuroprotective mechanisms. Given the ongoing global challenge in treating AD, researchers have increasingly focused on exploring the therapeutic potential of resveratrol.

摘要

白藜芦醇是一种具有生物活性的天然多酚植物产物。它具有多种特性,使其可用于治疗疾病。在本综述中,我们强调了白藜芦醇的神经保护作用。已经证明,几种现有的动物模型有助于通过白藜芦醇了解疾病的途径和作用机制。在本综述中,我们强调了白藜芦醇在 AD 中的神经保护活性,它通过减少斑块形成有效地抵抗神经退行性疾病。白藜芦醇是一种天然植物产物,易于获得,具有成本效益,并且具有神经保护活性,可用于治疗神经退行性疾病。由于其多种神经保护机制,白藜芦醇为 AD 治疗提供了有希望的途径。鉴于目前全球在治疗 AD 方面的挑战,研究人员越来越关注探索白藜芦醇的治疗潜力。

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