Liu Alice, Bauer Joshua S, Lin Chun-Chieh, Appelboom Geoff, Zanazzi George
Geisel School of Medicine, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, USA.
Department of Emergency Medicine, University of Iowa Hospitals and Clinics, Iowa City, USA.
Surg Neurol Int. 2024 Feb 23;15:55. doi: 10.25259/SNI_3_2024. eCollection 2024.
Composite hemangioendothelioma (CHE) is a rare, locally aggressive neoplasm of intermediate malignant potential. It is composed of a mixture of vascular tumors with a predilection for the dermis and subcutis of the extremities.
In this report, we describe a 41-year-old man who presented with a 2-month history of headache, dizziness, and intermittent seizures. Magnetic resonance imaging showed a hemorrhagic, multilobulated, and dural-based mass with extension into the calvarium. The mass measured 10.3 × 4.8 × 4 cm along the interhemispheric fissure and encased the superior sagittal sinus. Excision was performed, and histopathologic examination revealed a heterogeneous mixture of vascular components consisting of epithelioid hemangioendothelioma, retiform hemangioendothelioma, and hemangioma. This is the first report of a primary intracranial CHE.
The spectrum of mesenchymal neoplasms within the cranium expands to encompass CHE.
复合性血管内皮瘤（CHE）是一种罕见的、具有局部侵袭性且恶性潜能中等的肿瘤。它由多种血管肿瘤混合组成，好发于四肢的真皮和皮下组织。
在本报告中，我们描述了一名41岁男性，有2个月的头痛、头晕和间歇性癫痫病史。磁共振成像显示一个出血性、多叶状、基于硬脑膜的肿块，并延伸至颅骨。该肿块沿大脑镰裂长径为10.3×4.8×4厘米，包绕上矢状窦。进行了切除手术，组织病理学检查显示血管成分的异质性混合，包括上皮样血管内皮瘤、网状血管内皮瘤和血管瘤。这是原发性颅内CHE的首例报告。
颅骨内间叶性肿瘤的范围扩大到包括CHE。
Zotero 插件