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流产后发现一名患有独眼畸形的男性胎儿：叙利亚的一例罕见病例报告。

A male fetus with cyclopia was discovered after miscarriage: A rare case report from Syria.

作者信息

Dakkak Tala, Mansour Marah, Jarbouh Habib, Ktail Abdolmoin

机构信息

Faculty of Medicine Hama University Hama Syrian Arab Republic.

Faculty of Medicine Tartous University Tartous Syrian Arab Republic.

出版信息

Clin Case Rep. 2024 Mar 10;12(3):e8644. doi: 10.1002/ccr3.8644. eCollection 2024 Mar.

DOI:10.1002/ccr3.8644
PMID:38469129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10925722/
Abstract

KEY CLINICAL MESSAGE

This case of alobar holoprosencephaly and cyclopia emphasizes the value of prenatal check-ups, particularly in low-income countries. Early ultrasound diagnosis leads to early gestational termination, preventing psychological trauma for the parents.

ABSTRACT

Alobar holoprosencephaly is a rare-occurrence malformation with a bad prognosis linked to cyclopia, the most severe cranial feature. Prenatal examinations are essential for identifying these deformities and preventing parental mental health damage.

摘要

关键临床信息

这例无脑叶全前脑畸形及独眼畸形病例凸显了产前检查的重要性，尤其是在低收入国家。早期超声诊断可导致早期终止妊娠，避免给父母带来心理创伤。

摘要

无脑叶全前脑畸形是一种罕见的畸形，预后不良，与最严重的颅脑特征独眼畸形有关。产前检查对于识别这些畸形以及防止对父母心理健康造成损害至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad03/10925722/d7890e2eb079/CCR3-12-e8644-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad03/10925722/49b62b65695f/CCR3-12-e8644-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad03/10925722/4529e6799b25/CCR3-12-e8644-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad03/10925722/d7890e2eb079/CCR3-12-e8644-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad03/10925722/49b62b65695f/CCR3-12-e8644-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad03/10925722/4529e6799b25/CCR3-12-e8644-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad03/10925722/d7890e2eb079/CCR3-12-e8644-g003.jpg

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1
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Cyclopia and proboscis - the extreme end of holoprosencephaly.独眼畸形和鼻状畸形——前脑无裂畸形的极端表现。
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Sonic hedgehog signaling in craniofacial development. Sonic hedgehog 信号在颅面发育中的作用。
Differentiation. 2023 Sep-Oct;133:60-76. doi: 10.1016/j.diff.2023.07.002. Epub 2023 Jul 13.
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Cyclopia and proboscis - the extreme end of holoprosencephaly.独眼畸形和鼻状畸形——前脑无裂畸形的极端表现。
Rom J Morphol Embryol. 2017;58(4):1555-1559.
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Antenatal diagnosis of alobar holoprosencephaly.无脑叶全前脑畸形的产前诊断。
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Cyclopia syndrome.独眼畸形综合征
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