Becske Melinda, Lázár Imre, Bódizs Róbert
Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary.
Institute of Behavioural Sciences, Semmelweis University, Budapest, Hungary.
Sleep Biol Rhythms. 2022 Oct 20;21(2):155-163. doi: 10.1007/s41105-022-00426-0. eCollection 2023 Apr.
Subjects with high levels of attachment anxiety and neuroticism were proposed to be characterized by higher relative right rather than left frontal activity. Since sleep spindles are argued to reflect enhanced offline neuroplasticity, higher spindle activity measured over the right frontal areas relative to the corresponding left frontal ones could index higher attachment anxiety and neuroticism. Our aim was to explore the relationship between the lateralization patterns of frontally dominant slow sleep spindles and questionnaire measures of adult attachment anxiety and neuroticism. Thirty-four healthy subjects (male = 19; = 31.64; SD = 9.5) were enrolled in our preliminary study. Second night EEG/polysomnography records and questionnaire measures of personality (Zuckerman-Kuhlman Personality Questionnaire) and adult attachment (Relationship Scales Questionnaire) were collected. Frontal slow sleep spindles were measured by the Individual Adjustment Method (IAM), whereas hemispheric asymmetry indexes of spindle occurrence rate, duration, and amplitude were derived as normalized left-right differences (electrode pairs: Fp1-Fp2, F3-F4, and F7-F8). Relative right lateralization of frontolateral and frontopolar slow sleep spindle density and mid-frontal slow spindle duration were associated with attachment anxiety, but spindle lateralization was less closely related to neuroticism. The relationships between frontal slow spindle laterality and attachment anxiety remained statistically significant even after controlling for the effect of neuroticism, whereas attachment avoidance-independence was not correlated with frontal slow spindle lateralization. Right frontal lateralization of slow sleep spindle activity might indicate attachment status in terms of the negative view of the self.
The online version contains supplementary material available at 10.1007/s41105-022-00426-0.
有研究提出，具有高依恋焦虑水平和神经质的个体，其右侧额叶而非左侧额叶的相对活动水平更高。由于睡眠纺锤波被认为反映了离线神经可塑性的增强，相对于左侧额叶相应区域，右侧额叶区域测量到的更高纺锤波活动可能表明更高的依恋焦虑和神经质水平。我们的目的是探讨额叶主导的慢波睡眠纺锤波的偏侧化模式与成人依恋焦虑和神经质的问卷调查指标之间的关系。34名健康受试者（男性 = 19名；平均年龄 = 31.64岁；标准差 = 9.5岁）参与了我们的初步研究。收集了第二晚的脑电图/多导睡眠图记录以及人格（朱克曼 - 库尔曼人格问卷）和成人依恋（关系量表问卷）的问卷调查指标。采用个体调整法（IAM）测量额叶慢波睡眠纺锤波，而纺锤波发生率、持续时间和振幅的半球不对称指数则作为标准化的左右差异得出（电极对：Fp1 - Fp2、F3 - F4和F7 - F8）。额前和额极慢波睡眠纺锤波密度的相对右侧偏侧化以及额中慢波纺锤波持续时间与依恋焦虑相关，但纺锤波偏侧化与神经质的关系不太紧密。即使在控制了神经质的影响后，额叶慢波纺锤波偏侧化与依恋焦虑之间的关系仍具有统计学意义，而依恋回避 - 独立性与额叶慢波纺锤波偏侧化无关。慢波睡眠纺锤波活动的右侧额叶偏侧化可能从自我的负面观点方面表明依恋状态。
在线版本包含可在10.1007/s41105 - 022 - 00426 - 0获取的补充材料。
