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撤稿声明:由表皮生长因子受体(EGFR)途径调控的长链非编码RNA ABHD11-AS1通过表观遗传抑制金属蛋白酶组织抑制因子2(TIMP2)促进卵巢癌的肿瘤发生。

Retraction: lncRNA ABHD11-AS1, regulated by the EGFR pathway, contributes to the ovarian cancer tumorigenesis by epigenetically suppressing TIMP2.

出版信息

Cancer Med. 2024 Mar;13(5):e7098. doi: 10.1002/cam4.7098.

DOI:10.1002/cam4.7098
PMID:38470371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10929661/
Abstract

Xiang-Yang Zeng, Xiao-Yan Jiang, Jia-Hui Yong, Hui Xie, Jing Yuan, Da Zeng, Ying-Yu Dou, Song-Shu Xiao "lncRNA ABHD11-AS1, regulated by the EGFR pathway, contributes to the ovarian cancer tumorigenesis by epigenetically suppressing TIMP2" Cancer Med. 2019; 8: 7074-7085 (https://doi.org/10.1002/cam4.2586) The above article, published online on 30 September 2019, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal's Editor-in-Chief, Stephen Tait, and John Wiley and Sons Ltd. Following publication, concerns were raised by a third party regarding image overlap within Figure 2b. Furthermore, several figure elements have been published elsewhere, identifying the cells as originating from different cell lines and subjected to different treatment. The authors did not respond to the concerns raised and did not provide the original data. The editors consider the results and conclusion reported in this article unreliable.

摘要

曾向阳、蒋晓燕、雍家慧、谢辉、袁静、曾达、窦颖钰、肖松书 《长链非编码RNA ABHD11-AS1受EGFR通路调控,通过表观遗传抑制TIMP2促进卵巢癌肿瘤发生》 《癌症医学》。2019年;8:7074 - 7085(https://doi.org/10.1002/cam4.2586)上述文章于2019年9月30日在线发表于威利在线图书馆(wileyonlinelibrary.com),已应该期刊主编斯蒂芬·泰特与约翰·威利父子有限公司的协议撤稿。文章发表后,第三方对图2b中的图像重叠问题提出了担忧。此外,图中的几个元素已在其他地方发表过,显示这些细胞来自不同的细胞系并接受了不同的处理。作者未对提出的担忧做出回应,也未提供原始数据。编辑们认为本文报道的结果和结论不可靠。

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Long non‑coding RNA ABHD11‑AS1 inhibits colorectal cancer progression through interacting with EGFR to suppress the EGFR/ERK signaling pathway.长链非编码RNA ABHD11-AS1通过与表皮生长因子受体(EGFR)相互作用抑制EGFR/ERK信号通路,从而抑制结直肠癌进展。
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