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自杀倾向对迟发性创伤后应激障碍的影响因年龄而异:一项为期两年的纵向研究。

Impact of suicidality on delayed-onset post-traumatic stress disorder is modified by age: A two-year longitudinal study.

作者信息

Kim Jae-Min, Kim Ju-Wan, Kang Hee-Ju, Jang Hyunseok, Kim Jung-Chul, Chun Byung Jo, Lee Ju-Yeon, Kim Sung-Wan, Shin Il-Seon

机构信息

Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea.

Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea.

出版信息

J Affect Disord. 2024 Jun 1;354:51-54. doi: 10.1016/j.jad.2024.03.006. Epub 2024 Mar 11.

Abstract

OBJECTIVES

This study aimed to investigate the relationship between early suicidality and post-traumatic stress disorder (PTSD) onset in patients with physical injuries, focusing on age as a modifying factor.

METHODS

At baseline, 1014 patients were evaluated for suicidality, age divided into younger (<60 years) vs. older (≥60 years) groups, and potential covariates. PTSD was diagnosed at follow-up at 3, 6, 12, and 24 months, and then were categorized into early-onset (within the first six months after trauma) and delayed-onset (more than six months after trauma). Logistic regression models were used after adjusting for covariates.

RESULTS

Presence of suicidality at baseline was significantly associated with delayed-onset PTSD in older but not younger patients with significant interaction terms, whereas it was significantly associated with early-onset PTSD across all age groups.

CONCLUSION

Age-specific associations were found between suicidality and PTSD onset. The findings highlight the importance of early suicidality assessment, especially in older patients for ongoing monitoring and support, and underscore the critical need for early PTSD identification and intervention for all ages.

摘要

目的

本研究旨在调查身体受伤患者早期自杀倾向与创伤后应激障碍(PTSD)发病之间的关系,重点关注年龄作为一个调节因素。

方法

在基线时,对1014名患者进行自杀倾向评估,按年龄分为较年轻(<60岁)组和较年长(≥60岁)组,并评估潜在的协变量。在3、6、12和24个月的随访中诊断PTSD,然后将其分为早发型(创伤后前六个月内)和迟发型(创伤后六个月后)。在对协变量进行调整后使用逻辑回归模型。

结果

基线时存在自杀倾向与老年患者迟发型PTSD显著相关,但在年轻患者中无显著相关性,存在显著的交互作用项,而在所有年龄组中,自杀倾向与早发型PTSD显著相关。

结论

发现自杀倾向与PTSD发病之间存在年龄特异性关联。研究结果强调了早期自杀倾向评估的重要性,特别是对于老年患者进行持续监测和支持的重要性,并强调了对所有年龄段进行早期PTSD识别和干预的迫切需求。

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