Block A J
Dis Mon. 1985 May;31(5):1-56. doi: 10.1016/0011-5029(85)90032-x.
This article has ranged far and wide, from the pickwickian patient weighing 500 pounds to the tiny 4-lb premature baby, but the common thread is cessation or diminution of breathing during sleep and consequent oxygen desaturation. Associations have been made between abnormalities of sleep and breathing and multiple diseases--some causative and some fortuitous. Despite relating this information, we are only beginning to understand sleep and breathing. Although we spend a third of our lives asleep, very little attention was paid to the study of sleep until the mid 1970s. Even to this day, there is little interest in snoring and its adverse effects. The situation may be a sexist one in which men have done the research and the snoring, but the snoring has bothered only women. I predict that the next 15 years will see a vast increase both in studies of sleep and in our understanding of the importance of breathing during sleep--to the well-being of all of us.
本文涉猎广泛,从体重达500磅的匹克威克综合征患者到体重仅4磅的早产婴儿,但共同的主线是睡眠期间呼吸停止或减弱以及随之而来的氧饱和度下降。睡眠与呼吸异常和多种疾病之间存在关联——有些是因果关系,有些则是偶然的。尽管提供了这些信息,但我们才刚刚开始了解睡眠与呼吸。虽然我们一生中有三分之一的时间在睡觉,但直到20世纪70年代中期,睡眠研究才受到很少的关注。即使到今天,打鼾及其不良影响也很少受到关注。这种情况可能存在性别歧视,即男性进行了研究且打鼾,但打鼾困扰的却只有女性。我预测,在未来15年里,睡眠研究以及我们对睡眠期间呼吸对我们所有人健康的重要性的理解都将大幅增加。