Wang YuZhu, Jiang YunQi, Chen TingTing, Xia Qing, Wang XiaoFeng, Lv QianZhou, Li XiaoYu, Shao YunChao
Department of Pharmacy, Zhongshan Hospital Fudan University, 180# Feng Lin Road, Shanghai, 200032 Republic of China.
Department of Orthopedics, Zhongshan Hospital Fudan University, 180# Feng Lin Road, Shanghai, 200032 Republic of China.
Sleep Biol Rhythms. 2023 Aug 18;22(1):85-91. doi: 10.1007/s41105-023-00484-y. eCollection 2024 Jan.
The purpose of this study was to assess sleep quality in patients undergoing total hip arthroplasty (THA) from preoperatively to 12 weeks postoperatively and to establish a risk predictor for postoperative sleep disturbance to enable early care and intervention. A self-designed data collection form was used. Patients were assessed preoperatively and at 5 postoperative time points using visual analog scale (VAS) for pain, sleep quality and neuropsychological status with the following assessment tools: the Chinese versions of the Pittsburgh Sleep Quality Index (CPSQI), the Epworth Sleepiness Scale (CESS), the Zung Self-Rating Anxiety Scale (ZSAS) and the Epidemiological Studies Depression Scale (CESD). Univariate and multivariate logistic regression analysis was used for the identification of risk factors for postoperative sleep disturbance. The receiver operating characteristic (ROC) curve was plotted to evaluate the regression model. Of the 290 eligible patients, 193 (133 women) were included in the study. There was a 60.6% prevalence of preoperative sleep disturbance. The CPSQI score increased significantly at 2 weeks postoperatively compared to preoperative baseline, but appeared to decrease at 4 weeks postoperatively. Multivariate logistic regression analysis showed that pain (VAS score: OR = 1.202 [95% CI = 1.002-1.446, < 0.05]), daytime sleepiness (CESS score: OR = 1.134 [95% CI = 1.015-1.267, < 0.05]) and anxiety (ZSAS score: OR = 1.396 [95% CI = 1.184-1.645, < 0.001]) were risk factors associated with postoperative sleep disturbance at 2 weeks. The ROC curve showed that the AUC was 0.762, the sensitivity was 83.19% and the specificity was 64.86%. Postoperative sleep disturbance is highly prevalent in the first 2 weeks after THA. The risk prediction model constructed according to the above factors has good discriminant ability for the risk prediction of sleep disturbance after THA. The use of this risk prediction model can improve the recognition of patients and medical providers and has good ability to guide clinical nursing observation and early screening of sleep disturbance after THA.
本研究旨在评估全髋关节置换术(THA)患者术前至术后12周的睡眠质量,并建立术后睡眠障碍的风险预测模型,以便进行早期护理和干预。使用自行设计的数据收集表。采用视觉模拟量表(VAS)对患者术前及术后5个时间点的疼痛、睡眠质量和神经心理状态进行评估,评估工具如下:中文版匹兹堡睡眠质量指数(CPSQI)、爱泼华嗜睡量表(CESS)、zung自评焦虑量表(ZSAS)和流行病学研究抑郁量表(CESD)。采用单因素和多因素logistic回归分析确定术后睡眠障碍的危险因素。绘制受试者工作特征(ROC)曲线以评估回归模型。在290例符合条件的患者中,193例(133例女性)纳入研究。术前睡眠障碍患病率为60.6%。与术前基线相比,术后2周CPSQI评分显著升高,但术后4周似乎下降。多因素logistic回归分析显示,疼痛(VAS评分:OR = 1.202 [95%CI = 1.002 - 1.446,<0.05])、日间嗜睡(CESS评分:OR = 1.134 [95%CI = 1.015 - 1.267,<0.05])和焦虑(ZSAS评分:OR = 1.396 [95%CI = 1.184 - 1.645,<0.001])是术后2周睡眠障碍的相关危险因素。ROC曲线显示,AUC为0.762,敏感性为83.19%,特异性为64.86%。THA术后前2周睡眠障碍非常普遍。根据上述因素构建的风险预测模型对THA术后睡眠障碍的风险预测具有良好的判别能力。使用该风险预测模型可以提高患者和医护人员的识别能力,对指导THA术后临床护理观察和睡眠障碍早期筛查具有良好的能力。