Experimental bed rest as a model to investigate mechanisms of, and countermeasures against, microgravity and disease-free inactivity.

作者信息

Fernandez-Gonzalo Rodrigo, Deane Colleen S, Bailey Damian Miles

机构信息

Department of Laboratory Medicine, Division of Clinical Physiology, Karolinska Institutet, Stockholm, Sweden.

Unit of Clinical Physiology, Karolinska University Hospital, Stockholm, Sweden.

出版信息

Exp Physiol. 2024 May;109(5):647-649. doi: 10.1113/EP091795. Epub 2024 Mar 13.

DOI:10.1113/EP091795

PMID:38477070

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11061622/

Abstract

摘要

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本文引用的文献

[1]

Myths and Methodologies: Understanding the health impact of head down bedrest for the benefit of older adults and astronauts. Study protocol of the Canadian Bedrest Study.

Exp Physiol. 2024-5

[2]

Impact of 14 Days of Bed Rest in Older Adults and an Exercise Countermeasure on Body Composition, Muscle Strength, and Cardiovascular Function: Canadian Space Agency Standard Measures.

Gerontology. 2023

[3]

Canadian aging and inactivity study: Spaceflight-inspired exercises during head-down tilt bedrest blunted reductions in muscle-pump but not cardiac baroreflex in older persons.

Front Physiol. 2022-9-21

[4]

Bed rest and accelerated aging in relation to the musculoskeletal and cardiovascular systems and frailty biomarkers: A review.

Exp Gerontol. 2019-6-28

[5]

Long-duration bed rest as an analog to microgravity.

J Appl Physiol (1985). 2016-4-15

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Effects of immobilization upon various metabolic and physiologic functions of normal men.

Am J Med. 1948-1

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[30-day experiment in modelling the physiological effects of weightlessness].

Kosm Biol Med. 1972

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Experimental bed rest as a model to investigate mechanisms of, and countermeasures against, microgravity and disease-free inactivity.

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