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Double blind randomized controlled trial measuring the efficacy of nebulized steroid at half dose in comparison to high volume squeeze bottle steroid irrigation in management of patients with chronic rhinosinusitis.

作者信息

Megow Anna, Bouras George, Ooi Eng H, Vreugde Sarah, Psaltis Alkis, Wormald Peter-John

机构信息

Department of Surgery-Otolaryngology, Head and Neck Surgery, University of Adelaide, Adelaide, South Australia, Australia.

Department of Surgery-Otolaryngology, Head and Neck Surgery, Flinders Medical Centre, Adelaide, South Australia, Australia.

出版信息

Int Forum Allergy Rhinol. 2024 Aug;14(8):1375-1377. doi: 10.1002/alr.23336. Epub 2024 Mar 13.

DOI:10.1002/alr.23336
PMID:38477174
Abstract

Nebulized budesonide is effective at half dose compared to budesonide irrigation in CRS. Nasal nebulizers provide an alternative for delivery of topical steroids to the sinuses.

摘要

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Nasal irrigation solution is less cytotoxic to nasal epithelial cells than nasal spray.鼻腔冲洗液对鼻上皮细胞的细胞毒性低于鼻喷雾剂。
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