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美国人类遗传学简史。

A short history of human genetics in the USA.

作者信息

Reed S C

出版信息

Am J Med Genet. 1979;3(3):282-95. doi: 10.1002/ajmg.1320030308.

Abstract

The practicing physician discovered human genetics primarily as a result of two events. The use of the atomic bomb generated a vast amount of attention because of the fear of genetic hazards of radiation. Next, the discovery that the Down syndrome resulted from the presence of an extra chromosome finally focused the vision of the medical profession on human genetics as an area of importance in disease. It was also necessary that the erroneous fatalism about the impossibility of treating genetic diseases had to diminish before medicine would find human genetics attractive for research in therapeutic techniques. All of these things have come to pass and human genetics cannot help but enjoy a distinguished and extremely useful future.

摘要

执业医师发现人类遗传学主要源于两件事。原子弹的使用引发了大量关注,因为人们担心辐射的遗传危害。其次,唐氏综合征是由一条额外染色体的存在导致的这一发现,最终使医学界将目光聚焦于人类遗传学,视其为疾病领域的一个重要方面。在医学将人类遗传学视为治疗技术研究的有吸引力领域之前,关于无法治疗遗传疾病的错误宿命论也必须减少。所有这些都已成为现实,人类遗传学必将拥有卓越且极为有用的未来。

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