蛔虫与生长速率：一项治疗的随机试验
Ascaris and growth rates: a randomized trial of treatment.
作者信息
Willett W C, Kilama W L, Kihamia C M
出版信息
Am J Public Health. 1979 Oct;69(10):987-91. doi: 10.2105/ajph.69.10.987.
Abstract
Three hundred forty-one Tanzanian preschool children were randomly assigned to levamisole or placebo treatment given at three-month intervals. Weights and heights were measured at the tri-monthly treatment visits for a period of one year. Among the 273 children who were seen and weighed at the one-year follow-up visit, the rate of weight gain was 8 per cent greater for those receiving levamisole than for placebo-treated controls (p = .06). In 78 children known to be infected with Ascaris at baseline, the rate of weight gain was 21 per cent greater in children treated with levamisole than in those receiving placebo (p = .03). The rate of height gain was no different for treatment and placebo groups.
摘要
341名坦桑尼亚学龄前儿童被随机分配接受左旋咪唑或安慰剂治疗，治疗间隔为三个月。在为期一年的治疗期间，每三个月就诊时测量体重和身高。在一年随访就诊时接受检查和称重的273名儿童中，接受左旋咪唑治疗的儿童体重增加率比接受安慰剂治疗的对照组高8%（p = 0.06）。在基线时已知感染蛔虫的78名儿童中，接受左旋咪唑治疗的儿童体重增加率比接受安慰剂治疗的儿童高21%（p = 0.03）。治疗组和安慰剂组的身高增加率没有差异。
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