2020年至2022年中国高海拔地区感染新冠病毒的孕妇的分娩结局：一项回顾性分析
Birth Outcomes of Pregnant Women Infected with COVID-19 in Highland Areas of China from 2020 to 2022: A Retrospective Analysis.
作者信息
Lv Aiming, Ma Bian Ba Zhuo, Qiong De, Ma Da Wa Zhuo, Ma Pu Bu Zhuo, Yao Donghua, Zhen Da, Tang Chunxiu, Ma Bian Ba Zhuo, Lu Youzhi, Cai Long, Zhang Yutong, Yin Jinyu, Ding Tong, Zhen Lang Ji Qu, Cang Da Wa, Wu Meng, Chen Yulan, Li Ye
机构信息
Department of Obstetrics and Gynecology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
Department of Obstetrics and Gynecology, Women and Children's Hospital of Tibet Autonomous Region, Lhasa City, TB, People's Republic of China.
出版信息
Infect Drug Resist. 2024 Mar 8;17:927-934. doi: 10.2147/IDR.S435751. eCollection 2024.
PURPOSE
To explore the effect of coronavirus disease 2019 (COVID-19) infection on neonates in plateau regions.
METHODS
Cases of newborns born to pregnant women infected with COVID-19 who received prenatal care or treatment at the Women and Children's Hospital of the Tibet Autonomous Region and the Lhasa People's Hospital between January 2020 and December 2022 (infected group) and newborns born to healthy pregnant women (non-infected group) who were included by age, underlying disease and length of hospital stay were retrospectively collected. According to the inclusion and exclusion criteria, 381 patients in the infected group and 314 patients in the non-infected group were included in the study.
RESULTS
The results of multivariate analysis showed that admission to the neonatal intensive care unit (OR = 3.342, 95% CI = 1.564-6.764), shortness of breath (OR = 2.853, 95% CI = 1.789-3.154), irregular breathing (OR = 2.465, 95% CI = 1.879-4.112) and neonatal jaundice (OR = 2.324, 95% CI = 1.989-2.445) were the factors influencing the low Apgar scores of neonates in the infected group (all < 0.05).
CONCLUSION
Neonates born to pregnant women infected with COVID-19 had lower Apgar scores and higher incidences of complications, such as shortness of breath, groaning, irregular breathing and neonatal jaundice, than newborns born to pregnant women not infected with COVID-19.
目的
探讨2019冠状病毒病（COVID-19）感染对高原地区新生儿的影响。
方法
回顾性收集2020年1月至2022年12月期间在西藏自治区妇幼保健院和拉萨市人民医院接受产前检查或治疗的COVID-19感染孕妇所生新生儿病例（感染组），以及按年龄、基础疾病和住院时间纳入的健康孕妇所生新生儿（非感染组）。根据纳入和排除标准，感染组纳入381例患者，非感染组纳入314例患者。
结果
多因素分析结果显示，入住新生儿重症监护病房（OR = 3.342，95%CI = 1.564 - 6.764）、呼吸急促（OR = 2.853，95%CI = 1.789 - 3.154）、呼吸不规则（OR = 2.465，95%CI = 1.879 - 4.112）和新生儿黄疸（OR = 2.324，95%CI = 1.989 - 2.445）是影响感染组新生儿阿氏评分低的因素（均P < 0.05）。
结论
与未感染COVID-19的孕妇所生新生儿相比，感染COVID-19的孕妇所生新生儿阿氏评分较低，并发症发生率较高，如呼吸急促、呻吟、呼吸不规则和新生儿黄疸。
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