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一种在荷斯坦公牛站立去势过程中给予利多卡因的新型无针方法。

A novel needle-free method of lidocaine administration during standing castration of Holstein bulls.

作者信息

Curtis A K, Weeder M M, Martin M S, Leslie A A, Montgomery S R, Johnson B T, Coetzee J F, Lou M E, Viscardi A V, Kleinhenz M D

机构信息

Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66502.

Department of Clinical Science, Kansas State University, Manhattan, KS 66502.

出版信息

JDS Commun. 2023 Nov 17;5(2):150-154. doi: 10.3168/jdsc.2023-0459. eCollection 2024 Mar.

Abstract

The American Veterinary Medical Association recognizes castration to be important for both human and animal safety. Lidocaine delivered through-the-needle has been shown to be effective at reducing cortisol response to castration, but this method has drawbacks for both animals and caretakers. As such, a study was conducted to examine the potential benefits of lidocaine delivery using a pneumatic needle-free device immediately before standing bovine castration. Twelve Holstein bulls weighing 400.7 ± 39.5 kg (mean ± standard deviation) were enrolled. Bulls were allocated to receive a local anesthetic block of 2% lidocaine for surgical castration by traditional needle injection or by needle-free injection. Outcomes were collected out to 48 h postcastration. Outcome variables included plasma cortisol concentrations, visual analog scale scores for pain, medial canthus temperatures as measured using infrared thermography, pressure mat changes, and chute defense scores. A time effect was observed for cortisol, visual analog scale scores, infrared thermography temperatures, and some pressure mat outcomes. No statistically significant differences between lidocaine delivery methods were observed, but further research is needed to build upon this small dataset.

摘要

美国兽医协会认识到阉割对于人类和动物安全都很重要。经针给药的利多卡因已被证明能有效降低阉割引起的皮质醇反应,但这种方法对动物和饲养员都有缺点。因此,开展了一项研究,以检验在站立式牛阉割前立即使用气动无针装置给予利多卡因的潜在益处。纳入了12头体重为400.7±39.5千克(平均值±标准差)的荷斯坦公牛。公牛被分配接受通过传统针注射或无针注射给予的2%利多卡因局部麻醉阻滞用于手术阉割。在阉割后48小时收集结果。结果变量包括血浆皮质醇浓度、疼痛视觉模拟评分、使用红外热成像测量的内眦温度、压力垫变化和斜槽防御评分。观察到皮质醇、视觉模拟评分、红外热成像温度和一些压力垫结果存在时间效应。未观察到利多卡因给药方法之间有统计学显著差异,但需要基于这个小数据集进行进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ff8/10928437/e847fee6e1f6/fx1.jpg

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