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每年经皮冠状动脉介入治疗慢性完全闭塞病变的术者手术量和手术结果分析:基于 14899 例患者的研究。

Annual operator volume and procedural outcomes of chronic total occlusions treated with percutaneous coronary interventions: analysis based on 14,899 patients.

机构信息

Department of Cardiology and Cardiovascular Interventions, University Hospital, Kraków, Poland -

Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Cracow University, Kraków, Poland -

出版信息

Minerva Cardiol Angiol. 2024 Aug;72(4):336-345. doi: 10.23736/S2724-5683.23.06447-5. Epub 2024 Mar 14.

DOI:10.23736/S2724-5683.23.06447-5
PMID:38482633
Abstract

BACKGROUND

Low operator and institutional volume is associated with poorer procedural and long-term clinical outcomes in patients treated with percutaneous coronary interventions (PCI). This study was aimed at evaluating the relationship between operator volume and procedural outcomes of patients treated with PCI for chronic total occlusion (CTO).

METHODS

Data were obtained from the national registry of percutaneous coronary interventions (ORPKI) collected from January 2014 to December 2020. The primary endpoint was a procedural success, defined as restoration of thrombolysis in myocardial infarction (TIMI) II/III flow without in-hospital cardiac death and myocardial infarction, whereas secondary endpoints included periprocedural complications.

RESULTS

Data of 14,899 CTO-PCIs were analyzed. The global procedural success was 66.1%. There was a direct relationship between the annual volume of CTO-PCIs per operator and the procedural success (OR: 1.006 [95% CI: 1.003-1.009]; P<0.001). The nonlinear relationships of annualized CTO-PCI volume per operator and adjusted outcome rates revealed that operators performing 40 CTO cases per year had the best procedural outcomes in terms of technical success (TIMI flow II/III after PCI), coronary artery perforation rate and any periprocedural complications rate (P<0.0001). Among the other factors associated with procedural success, the following can be noted: multi-vessel, left main coronary artery disease (as compared to single-vessel disease), the usage of rotablation as well as PCI within bifurcation.

CONCLUSIONS

High-volume CTO operators achieve greater procedural success with a lower frequency of periprocedural complications. Higher annual caseload might increase the overall quality of CTO-PCI.

摘要

背景

在接受经皮冠状动脉介入治疗(PCI)的患者中,术者和机构的低手术量与较差的手术过程和长期临床结果相关。本研究旨在评估术者手术量与接受 PCI 治疗慢性完全闭塞(CTO)患者的手术结果之间的关系。

方法

数据来自 2014 年 1 月至 2020 年 12 月期间全国经皮冠状动脉介入治疗登记(ORPKI)。主要终点是手术成功率,定义为心肌梗死溶栓治疗(TIMI)血流 II/III 级恢复,无院内死亡和心肌梗死,次要终点包括围手术期并发症。

结果

分析了 14899 例 CTO-PCI 的数据。全球手术成功率为 66.1%。术者每年 CTO-PCI 量与手术成功率之间存在直接关系(OR:1.006[95%CI:1.003-1.009];P<0.001)。术者每年 CTO-PCI 量的年化与调整后结局率的非线性关系表明,每年进行 40 例 CTO 病例的术者在技术成功率(PCI 后 TIMI 血流 II/III)、冠状动脉穿孔率和任何围手术期并发症发生率方面具有最佳的手术结果(P<0.0001)。在与手术成功率相关的其他因素中,可以注意到以下几点:多血管病变、左主干冠状动脉疾病(与单血管病变相比)、使用旋磨术以及分叉处的 PCI。

结论

高手术量 CTO 术者的手术成功率更高,围手术期并发症的发生频率更低。较高的年手术量可能会提高 CTO-PCI 的整体质量。

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