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微粒体乙醇氧化系统的光化学作用光谱。

The photochemical action spectrum of the microsomal ethanol oxidizing system.

作者信息

Fabry T L, Lieber C S

出版信息

Alcohol Clin Exp Res. 1979 Jul;3(3):219-22. doi: 10.1111/j.1530-0277.1979.tb05303.x.

DOI:10.1111/j.1530-0277.1979.tb05303.x
PMID:384830
Abstract

The inhibition of the microsomal ethanol oxidizing system (MEOS) by carbon monoxide (CO) can be reversed by illumination with lights of differing wavelengths. The authors determined the efficiency of this reversal as a function of the illuminating light. Maximum efficiency was obtained in the wavelength band around 440-450 nm, which is near the absorption of the reduced cytochrome-P-450-carbon monoxide complex. When the experiment was repeated with microsomes prepared from ethanol-fed rats, the wavelength for maximum efficiency shifted towards higher values.

摘要

一氧化碳(CO)对微粒体乙醇氧化系统(MEOS)的抑制作用可通过不同波长的光照来逆转。作者测定了这种逆转效率与照明光的函数关系。在440 - 450nm左右的波段获得了最大效率,该波段接近还原型细胞色素P - 450 - 一氧化碳复合物的吸收峰。当用由乙醇喂养的大鼠制备的微粒体重复该实验时,最大效率对应的波长向更高值移动。

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