Wang Y F, Chen C S, Girdaukas G, Sih C J
Ciba Found Symp. 1985;111:128-45. doi: 10.1002/9780470720929.ch10.
A strategy for expanding the applicability of esterases of low enantioselectivity for asymmetric synthesis is described. This concept is generally applicable to biochemical processes involving enantiotopic group differentiation. Quantitative expressions have been derived to permit the prediction of enantiomeric excess and the optimization of optical and chemical yields.
描述了一种扩大低对映选择性酯酶在不对称合成中适用性的策略。这一概念通常适用于涉及对映异位基团区分的生化过程。已经推导出定量表达式,以预测对映体过量并优化光学产率和化学产率。