Sidney Kimmel Medical College at Thomas Jefferson University at Thomas Jefferson University.
Wills Eye Hospital, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania.
Curr Opin Ophthalmol. 2024 May 1;35(3):225-231. doi: 10.1097/ICU.0000000000001032. Epub 2024 Mar 13.
The field of corneal biomechanics has rapidly progressed in recent years, reflecting technological advances and an increased understanding of the clinical significance of measuring these properties. This review will evaluate in-vivo biomechanical properties obtained by current technologies and compare them regarding their relevance to established biomechanical properties obtained by gold-standard ex-vivo techniques normally conducted on elastic materials.
Several new technologies have appeared in recent years, including vibrational optical coherence tomography (VOCT) and the corneal indentation device (CID). These techniques provide promising new opportunities for minimally invasive and accurate measurements of corneal viscoelastic properties.
Alterations in corneal biomechanics are known to occur in several corneal degenerative diseases and after refractive surgical procedures. The measurement of corneal biomechanical properties has the capability to diagnose early disease and monitor corneal disease progression. Several new technologies have emerged in recent years, allowing for more accurate and less invasive measurements of corneal biomechanical properties, most notably the elastic modulus.
近年来,角膜生物力学领域发展迅速,这反映了技术的进步和对测量这些特性的临床意义的理解的提高。本文将评估当前技术获得的活体生物力学特性,并比较它们与通常在弹性材料上进行的金标准离体技术获得的已确立的生物力学特性的相关性。
近年来出现了几种新技术,包括振动光学相干断层扫描(VOCT)和角膜压痕仪(CID)。这些技术为角膜粘弹性特性的微创和准确测量提供了有前途的新机会。
已知几种角膜退行性疾病和屈光手术后角膜生物力学发生改变。角膜生物力学特性的测量具有诊断早期疾病和监测角膜疾病进展的能力。近年来出现了几种新技术,使得对角膜生物力学特性的更准确和微创测量成为可能,尤其是弹性模量。