Alfaifi Amal J, Wasli Ohood S, Almalki Thamer M, Alqassim Ahmad Y
Family Medicine, Jazan Health Cluster, Jazan, SAU.
Family Medicine, Armed Forces Hospital, Jazan, SAU.
Cureus. 2024 Feb 13;16(2):e54128. doi: 10.7759/cureus.54128. eCollection 2024 Feb.
Trigeminal neuralgia (TN) is characterized by episodic electric, shock-like facial pain. Though often idiopathic, herpes simplex virus type 1 (HSV-1) reactivation can rarely cause symptomatic TN. We report the case of a 30-year-old woman who developed oral HSV-1 lesions followed by right-sided TN pain. MRI of the brain did not reveal neurovascular compression. TN pain completely resolved with oral acyclovir treatment alone, without anticonvulsants. This highlights the importance of considering atypical etiologies such as HSV-1 reactivation in TN evaluation. Early antiviral therapy may treat underlying inflammation and provide sustained symptom relief in HSV-associated TN.
三叉神经痛（TN）的特征是发作性电击样面部疼痛。虽然通常为特发性，但1型单纯疱疹病毒（HSV-1）再激活很少会导致症状性TN。我们报告了一例30岁女性病例，该患者先出现口腔HSV-1病变，随后出现右侧TN疼痛。脑部MRI未显示神经血管受压。仅口服阿昔洛韦治疗，未使用抗惊厥药物，TN疼痛就完全缓解。这突出了在TN评估中考虑HSV-1再激活等非典型病因的重要性。早期抗病毒治疗可能会治疗潜在炎症，并为HSV相关的TN提供持续的症状缓解。
