Cardona-Cardona Andrés F, Mumtaz Sehreen, Balistreri Lisa, Stanbourough Rupert, Butendieck Ronald, Wang Benjamin, Abril Andy, Vikas Majithia, Berianu Florentina
Rheumatology, Universidad de Antioquia, Medellín, COL.
Rheumatology, Mayo Clinic Florida, Jacksonville, USA.
Cureus. 2024 Feb 12;16(2):e54086. doi: 10.7759/cureus.54086. eCollection 2024 Feb.
Neurosarcoidosis is one of the most relevant involvements in systemic sarcoidosis and can be the initial presentation. Its diagnosis is often considered difficult because of unusual clinical manifestations or diagnostic mimics. The peripheral nervous system is less frequently involved than the central nervous system, although it may also lead to irreversible neurologic impairment. Lumbosacral plexopathy in sarcoidosis is a rare presentation and has been scarcely described in anecdotal case reports and small case series. We describe the case of a 61-year-old female who presented with right inguinal pain, right thigh weakness, and gait limitation, with imaging evidence of bilateral lumbosacral plexopathy as the initial manifestation of systemic sarcoidosis and subsequently developed joint and pulmonary involvement. This case report aims to bring awareness of this involvement as a possible initial manifestation of systemic sarcoidosis and mention key features of the differential diagnosis. Prompt recognition and treatment may prevent neurologic impairment.
神经结节病是系统性结节病最常见的累及部位之一，也可能是首发表现。由于临床表现不寻常或存在诊断上的相似情况，其诊断通常被认为具有挑战性。尽管周围神经系统受累也可能导致不可逆的神经功能损害，但相较于中枢神经系统，其受累情况相对少见。结节病引起的腰骶丛神经病是一种罕见的表现，在零星的病例报告和小病例系列中鲜有描述。我们报告了一例61岁女性患者，以右腹股沟疼痛、右大腿无力和步态受限为表现，影像学证据显示双侧腰骶丛神经病是系统性结节病的首发表现，随后出现关节和肺部受累。本病例报告旨在提高对这种作为系统性结节病可能首发表现的认识，并提及鉴别诊断的关键特征。及时识别和治疗可能预防神经功能损害。
