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Single-cell sequencing reveals alterations in the peripheral blood mononuclear cell landscape and monocyte status during colorectal adenocarcinoma formation.

作者信息

Xu Jiasheng, Hu Yeting, Zhao Jie, Kong Xiangxing, Xia Sijian, Dai Siqi, Ding Lei, Bu Tongtong, Cao Yue, Liu Manjiao, Yan Linlin, Xiao Qian, Guo Hao, Yuan Ying, Xu Dong, Ding Kefeng

机构信息

Department of Colorectal Surgery, The Second Hospital of Zhejiang University School of Medicine (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, and Key Laboratory of Medical Molecular Biology), Zhejiang University, Hangzhou, China.

Zhejiang University Cancer Institute, Hangzhou, China.

出版信息

Clin Transl Med. 2024 Mar;14(3):e1609. doi: 10.1002/ctm2.1609.

DOI:10.1002/ctm2.1609
PMID:38488463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10941536/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9cb/10941536/1b7c963fd4fa/CTM2-14-e1609-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9cb/10941536/f81dce2574ad/CTM2-14-e1609-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9cb/10941536/423a5d7b0457/CTM2-14-e1609-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9cb/10941536/15e9eb2173bd/CTM2-14-e1609-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9cb/10941536/1b7c963fd4fa/CTM2-14-e1609-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9cb/10941536/f81dce2574ad/CTM2-14-e1609-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9cb/10941536/423a5d7b0457/CTM2-14-e1609-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9cb/10941536/15e9eb2173bd/CTM2-14-e1609-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9cb/10941536/1b7c963fd4fa/CTM2-14-e1609-g001.jpg

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本文引用的文献

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InterCellar enables interactive analysis and exploration of cell-cell communication in single-cell transcriptomic data.InterCellar 能够对单细胞转录组数据中的细胞间通讯进行交互式分析和探索。
Commun Biol. 2022 Jan 11;5(1):21. doi: 10.1038/s42003-021-02986-2.
2
Alterations of circulating lymphocyte subsets in patients with colorectal carcinoma.结直肠癌患者循环淋巴细胞亚群的改变。
Cancer Immunol Immunother. 2022 Aug;71(8):1937-1947. doi: 10.1007/s00262-021-03127-8. Epub 2021 Dec 20.
3
Immunotherapy in colorectal cancer: current achievements and future perspective.
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Int J Biol Sci. 2021 Sep 3;17(14):3837-3849. doi: 10.7150/ijbs.64077. eCollection 2021.
4
Global colorectal cancer burden in 2020 and projections to 2040.2020年全球结直肠癌负担及到2040年的预测。
Transl Oncol. 2021 Oct;14(10):101174. doi: 10.1016/j.tranon.2021.101174. Epub 2021 Jul 6.
5
Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients.外周血单核细胞单细胞测序揭示 COVID-19 和流感患者不同的免疫反应图谱。
Immunity. 2020 Sep 15;53(3):685-696.e3. doi: 10.1016/j.immuni.2020.07.009. Epub 2020 Jul 19.
6
CellPhoneDB: inferring cell-cell communication from combined expression of multi-subunit ligand-receptor complexes.CellPhoneDB：从多亚基配体-受体复合物的综合表达推断细胞间通讯。
Nat Protoc. 2020 Apr;15(4):1484-1506. doi: 10.1038/s41596-020-0292-x. Epub 2020 Feb 26.
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Evolving notions on immune response in colorectal cancer and their implications for biomarker development.结直肠癌中免疫反应的不断发展的观念及其对生物标志物开发的影响。
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