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Status of biomarker development for frontotemporal dementia and amyotrophic lateral sclerosis.

作者信息

Yang Yue, Cheng Qi, Gao Jianqun, Kim Woojin Scott

机构信息

Brain and Mind Centre & School of Medical Sciences, The University of Sydney, Sydney, NSW, Australia.

Department of Neurology and Neurophysiology, Liverpool Hospital, Sydney, NSW, Australia.

出版信息

Neural Regen Res. 2024 Oct 1;19(10):2117-2118. doi: 10.4103/1673-5374.392883. Epub 2024 Jan 8.

DOI:10.4103/1673-5374.392883
PMID:38488546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11034604/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1847/11034604/865d564249ae/NRR-19-2117-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1847/11034604/865d564249ae/NRR-19-2117-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1847/11034604/865d564249ae/NRR-19-2117-g001.jpg

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本文引用的文献

1
Relationship between CSF tau biomarkers and structural brain MRI measures in frontotemporal lobar degeneration.脑脊液 tau 生物标志物与额颞叶变性的结构脑 MRI 测量之间的关系。
J Neurol Sci. 2022 Nov 15;442:120415. doi: 10.1016/j.jns.2022.120415. Epub 2022 Sep 8.
2
Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study.遗传性额颞叶痴呆患者脑脊液和血浆补体蛋白升高:来自 GENFI 研究的结果。
J Neuroinflammation. 2022 Sep 5;19(1):217. doi: 10.1186/s12974-022-02573-0.
3
Serum GFAP differentiates Alzheimer's disease from frontotemporal dementia and predicts MCI-to-dementia conversion.
血清胶质纤维酸性蛋白可区分阿尔茨海默病与额颞叶痴呆,并预测轻度认知障碍向痴呆的转化。
J Neurol Neurosurg Psychiatry. 2022 Apr 27. doi: 10.1136/jnnp-2021-328547.
4
Neurofilaments can differentiate ALS subgroups and ALS from common diagnostic mimics.神经丝可以区分 ALS 亚组和 ALS 与常见诊断性类似物。
Sci Rep. 2021 Nov 11;11(1):22128. doi: 10.1038/s41598-021-01499-6.
5
Phase 1b dose-escalation, safety, and pharmacokinetic study of IC14, a monoclonal antibody against CD14, for the treatment of amyotrophic lateral sclerosis.针对肌萎缩侧索硬化症的 CD14 单克隆抗体 IC14 的 1b 期剂量递增、安全性和药代动力学研究。
Medicine (Baltimore). 2021 Oct 22;100(42):e27421. doi: 10.1097/MD.0000000000027421.
6
Neurofilament light and heterogeneity of disease progression in amyotrophic lateral sclerosis: development and validation of a prediction model to improve interventional trials.神经丝轻链与肌萎缩侧索硬化症疾病进展的异质性:一种改进干预试验的预测模型的开发和验证。
Transl Neurodegener. 2021 Aug 26;10(1):31. doi: 10.1186/s40035-021-00257-y.
7
CSF sTREM2 is elevated in a subset in GRN-related frontotemporal dementia.脑脊液 sTREM2 在部分 GRN 相关额颞叶痴呆患者中升高。
Neurobiol Aging. 2021 Jul;103:158.e1-158.e5. doi: 10.1016/j.neurobiolaging.2021.02.024. Epub 2021 Mar 4.
8
CSF Neurofilament Light Chain Elevation Predicts ALS Severity and Progression.脑脊液神经丝轻链升高可预测肌萎缩侧索硬化症的严重程度和进展。
Front Neurol. 2020 Aug 28;11:919. doi: 10.3389/fneur.2020.00919. eCollection 2020.
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Altered levels of CSF proteins in patients with FTD, presymptomatic mutation carriers and non-carriers.额颞叶痴呆患者、症状前突变携带者和非携带者脑脊液蛋白水平改变。
Transl Neurodegener. 2020 Jun 23;9(1):27. doi: 10.1186/s40035-020-00198-y.
10
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J Neurol Neurosurg Psychiatry. 2019 Dec;90(12):1338-1346. doi: 10.1136/jnnp-2018-319586. Epub 2019 Jun 7.