Ophthalmology Department, Pamukkale University, 20070, Denizli, Turkey.
Rheumatology Division, İzzet Baysal Training and Research Hospital, Bolu, Turkey.
Int Ophthalmol. 2024 Mar 15;44(1):137. doi: 10.1007/s10792-024-03013-z.
To evaluate the thickness of anterior sclera and corneal layers in patients with systemic sclerosis.
The present cross-sectional study included 41 patients with systemic sclerosis and 41 age- and gender-matched healthy controls. The study and control groups were compared in terms of the thickness of anterior sclera, corneal epithelium, Bowman's layer, corneal stroma, and Descemet's membrane-endothelium complex. The thickness measurements were obtained using the anterior segment module of spectral-domain optical coherence tomography.
The thickness of anterior sclera, corneal epithelium, Bowman's layer, and Descemet's membrane-endothelium complex were similar in the patients with systemic sclerosis and healthy controls (P > 0.05). Total corneal thickness at the apex was 511.1 ± 33.5 µm in the systemic sclerosis group and 528.4 ± 29.5 µm in the control group (P = 0.015). The corneal stroma was thinner in the systemic sclerosis patients compared to the healthy controls (P = 0.02).
The corneal stroma was thinner in the patients with systemic sclerosis compared to that of healthy controls, while the thickness of the anterior sclera was similar in both groups.
评估系统性硬化症患者前巩膜和角膜各层的厚度。
本横断面研究纳入了 41 例系统性硬化症患者和 41 名年龄和性别匹配的健康对照者。比较了前巩膜、角膜上皮、Bowman 层、角膜基质和 Descemet 膜-内皮复合体的厚度。使用频域光学相干断层扫描的眼前节模块进行厚度测量。
系统性硬化症患者与健康对照组在前巩膜、角膜上皮、Bowman 层和 Descemet 膜-内皮复合体的厚度方面无差异（P＞0.05）。系统性硬化症组顶点处总角膜厚度为 511.1±33.5μm，对照组为 528.4±29.5μm（P=0.015）。与健康对照组相比，系统性硬化症患者的角膜基质更薄（P=0.02）。
与健康对照组相比，系统性硬化症患者的角膜基质更薄，而两组的前巩膜厚度相似。
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