• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

量化时间相关单光子计数中的失真:一个通用参数。

Quantifying distortion in time-correlated single photon counting: a universal parameter.

作者信息

Bovolenta Angela, Cominelli Alessandro, Acconcia Giulia, Rech Ivan

出版信息

Opt Lett. 2024 Mar 15;49(6):1563-1566. doi: 10.1364/OL.511914.

DOI:10.1364/OL.511914
PMID:38489451
Abstract

One major drawback of the classic time-correlated single photon counting (TCSPC) technique is pileup-related distortion. To keep it under a reasonable level, the maximum count rate has to be reduced, posing a serious limitation to the overall measurement speed. This means that there is an intrinsic trade-off between speed and distortion: either count rate is raised, but distortion is worsened, or distortion is minimized at the expense of speed. In both cases, it is impossible to precisely evaluate the degree of distortion introduced. Here comes our new, to the best of our knowledge, figure of merit, which is able to provide a numerical estimate of the distortion whatever the signal shape is, marking a real turning point in the way of doing TCSPC. In this article, this new parameter will be defined and its effectiveness will be demonstrated by means of mathematical computations.

摘要

经典的时间相关单光子计数(TCSPC)技术的一个主要缺点是与堆积相关的失真。为了将其保持在合理水平,必须降低最大计数率,这对整体测量速度造成了严重限制。这意味着在速度和失真之间存在内在的权衡:要么提高计数率,但失真会恶化,要么以速度为代价将失真最小化。在这两种情况下,都无法精确评估引入的失真程度。据我们所知,这就是我们新的品质因数,无论信号形状如何,它都能够提供失真的数值估计,这标志着TCSPC方法的一个真正转折点。在本文中,将定义这个新参数,并通过数学计算证明其有效性。

相似文献

1
Quantifying distortion in time-correlated single photon counting: a universal parameter.量化时间相关单光子计数中的失真:一个通用参数。
Opt Lett. 2024 Mar 15;49(6):1563-1566. doi: 10.1364/OL.511914.
2
Near-zero distortion in TCSPC at more than one photon per excitation period: experimental validation.在每个激发周期有多个光子的情况下,时间相关单光子计数(TCSPC)中的近零失真:实验验证
Opt Lett. 2024 Sep 1;49(17):4958-4961. doi: 10.1364/OL.534363.
3
High-speed and low-distortion solution for time-correlated single photon counting measurements: A theoretical analysis.用于时间相关单光子计数测量的高速低失真解决方案:理论分析
Rev Sci Instrum. 2017 Dec;88(12):123701. doi: 10.1063/1.4996690.
4
Fast fully-integrated front-end circuit to overcome pile-up limits in time-correlated single photon counting with single photon avalanche diodes.快速全集成前端电路,以克服单光子雪崩二极管在时间相关单光子计数中的堆积限制。
Opt Express. 2018 Jun 11;26(12):15398-15410. doi: 10.1364/OE.26.015398.
5
Above pile-up fluorescence microscopy with a 32 Mc/s single-channel time-resolved SPAD system.采用32 Mc/s单通道时间分辨单光子雪崩二极管(SPAD)系统的超高堆积荧光显微镜。
Opt Lett. 2022 Jan 1;47(1):82-85. doi: 10.1364/OL.444815.
6
Pulse pileup statistics for energy discriminating photon counting x-ray detectors.用于能量甄别光子计数 X 射线探测器的脉冲堆积统计。
Med Phys. 2011 Jul;38(7):4265-75. doi: 10.1118/1.3592932.
7
Achieving a high photon count rate in digital time-correlated single photon counting using a hybrid photodetector.使用混合光电探测器在数字时间相关单光子计数中实现高光子计数率。
Opt Express. 2021 Mar 29;29(7):9797-9804. doi: 10.1364/OE.419896.
8
Direct energy binning for photon counting detectors: Simulation study.直接能量-bin 技术在光子计数探测器中的应用:模拟研究。
Med Phys. 2024 Jan;51(1):70-79. doi: 10.1002/mp.16841. Epub 2023 Nov 27.
9
Assessment of multi-energy inter-pixel coincidence counters for photon-counting detectors at the presence of charge sharing and pulse pileup: A simulation study.评估存在电荷共享和脉冲堆积时光子计数探测器的多能量像素间符合计数器:一项模拟研究。
Med Phys. 2021 Sep;48(9):4909-4925. doi: 10.1002/mp.15112. Epub 2021 Aug 2.
10
Toward ultra-fast time-correlated single-photon counting: A compact module to surpass the pile-up limit.迈向超快速时间相关单光子计数:一个超越堆积极限的紧凑型模块。
Rev Sci Instrum. 2021 Jun 1;92(6):063702. doi: 10.1063/5.0044774.

引用本文的文献

1
A low-cost FPGA-based approach for pile-up corrected high-speed FLIM imaging.一种基于低成本现场可编程门阵列的堆积校正高速荧光寿命成像方法。
Neurophotonics. 2025 Apr;12(2):025009. doi: 10.1117/1.NPh.12.2.025009. Epub 2025 May 5.