University of Texas Southwestern Medical Center, Dallas TX.
Urology. 2024 Aug;190:133-139. doi: 10.1016/j.urology.2024.03.016. Epub 2024 Mar 13.
To assess surgical success and patient-reported outcomes of perineal urethrostomy via midline approach.
Charts of patients undergoing primary perineal urethrostomy between May 2008 and June 2022 were reviewed. Background characteristics were assessed; success was defined as freedom from re-intervention. Patient-reported outcome measures were assessed using a cross-sectional phone survey. Several validated questionnaires were used to assess lower urinary tract symptoms, quality of life, and erectile dysfunction.
Among 1768 urethroplasties performed over the study period, 103 patients (5.8%) underwent midline perineal urethrostomy. Surgery was successful in 95.1% of cases (98/103); 5 patients (4.9%) required re-intervention at a median of 8.7 months. Post-operative complications occurred in 5.8% of cases (6/103) and were both mild and self-limited. Forty-nine patients (47.6%) were reached via phone survey at a median of 61 months post-operatively. Some questions were not answered by all patients. Most patients (42/49, 86%) were satisfied or very satisfied with surgical results, and 82% (40/49) reported an improvement in their overall health. Most patients (31/41, 76%) were unbothered by sitting to urinate. Although 20% of patients (10/49) reported post-operative urinary symptoms that interfered "a lot" with their daily life, only 3 (6%) of these patients reported dissatisfaction with the outcome. Regarding sexual function, 64% (27/42) reported indifference to or increased satisfaction with sexual encounters vs before surgery. The rate of de novo erectile dysfunction was 24% (12/49).
The midline approach to perineal urethrostomy provides excellent, durable success rates with high levels of patient satisfaction.
评估经中线入路行会阴尿道吻合术的手术成功率和患者报告的结局。
回顾 2008 年 5 月至 2022 年 6 月期间行初次会阴尿道吻合术的患者的病历资料。评估背景特征;手术成功定义为无需再次干预。采用横断面电话调查评估患者报告的结局测量指标。使用几种经过验证的问卷评估下尿路症状、生活质量和勃起功能障碍。
在研究期间行的 1768 例尿道成形术中,有 103 例(5.8%)行中线会阴尿道吻合术。95.1%(98/103)的病例手术成功;5 例(4.9%)患者在中位 8.7 个月时需要再次干预。5.8%(6/103)的病例发生术后并发症,均为轻度且自限性。术后中位 61 个月时,通过电话调查联系到 49 例(47.6%)患者。并非所有患者都回答了所有问题。大多数患者(42/49,86%)对手术结果满意或非常满意,82%(40/49)报告整体健康状况改善。大多数患者(31/41,76%)对排尿时坐立无碍感到满意。虽然 20%(10/49)的患者报告术后尿症状“非常多”地干扰日常生活,但只有 3 例(6%)患者对结局不满意。关于性功能,64%(27/42)的患者报告与手术前相比对性接触漠不关心或更满意。新发勃起功能障碍的发生率为 24%(12/49)。
会阴尿道吻合术经中线入路可获得极佳、持久的成功率,且患者满意度高。