Department of Pulmonary & Critical Care, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Department of Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles, CA, United States.
Diagn Microbiol Infect Dis. 2024 Jun;109(2):116251. doi: 10.1016/j.diagmicrobio.2024.116251. Epub 2024 Mar 8.
A 61-year-old male with subacute headache was found to have cryptococcal meningitis despite a negative BioFire FilmArray meningitis/encephalitis panel. This case underscores the importance of liberal cryptococcal antigen testing, and that a negative FilmArray panel is inadequate in excluding cryptococcal meningitis, particularly in a HIV-negative host.
一位 61 岁男性亚急性头痛,尽管生物梅里埃 FilmArray 脑膜炎/脑炎 panel 检测结果为阴性,仍被诊断为隐球菌性脑膜炎。这个病例强调了进行广泛的隐球菌抗原检测的重要性,以及 FilmArray 检测结果为阴性并不能充分排除隐球菌性脑膜炎,尤其是在 HIV 阴性宿主中。