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患有阿片类药物使用障碍和创伤后应激症状的女性的生活体验和治疗需求:一项混合方法研究。

The lived experiences and treatment needs of women with opioid use disorder and posttraumatic stress symptoms: A mixed methods study.

机构信息

Center of Alcohol & Substance Use Studies, Rutgers University, New Brunswick, New Jersey, United States of America; Department of Psychiatry & Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, United States of America.

Department of Psychiatry & Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, United States of America; George Washington University, Washington D.C.

出版信息

J Subst Use Addict Treat. 2024 Jun;161:209344. doi: 10.1016/j.josat.2024.209344. Epub 2024 Mar 15.

DOI:10.1016/j.josat.2024.209344
PMID:38492805
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11146521/
Abstract

INTRODUCTION

Women show a gender-specific risk for co-occurring opioid use disorder (OUD) and posttraumatic stress disorder (PTSD). Expert groups have called for the development of integrated treatments for women with OUD/PTSD, but there remains limited information on such interventions.

METHODS

This mixed-methods study interviewed and surveyed 10 women with current or past OUD and co-occurring posttraumatic stress symptoms (PTSS) and 16 providers who work with these women. Interviews and surveys queried patient participants' and providers' experiences of OUD/PTSS and how to best design an integrated, trauma-focused treatment for OUD/PTSD.

RESULTS

Patient participants (90 % white, 90 % mothers, M = 45.70) met criteria for severe, lifetime OUD and 40 % met a provisional diagnosis for PTSD. Four themes emerged for participants' experiences of OUD/PTSS: 1) numerous stressors; 2) shame; 3) multiple motivations to use opioids; and 4) a cycle of trauma and opioid use. Four themes emerged regarding patient participants' perceptions on the development of an OUD/PTSD treatment: 1) mixed attitudes towards medications for OUD; 2) barriers to treatment (e.g., insufficient treatments and contextual factors); 3) treatment facilitators (e.g., social support); and 4) preferences in treatment (e.g., trauma-focused, gender-focused, family content, ambivalence around group therapy). Providers (M = 38.94) were primarily white women (76.5 %). Two themes emerged from their experiences working with women with OUD/PTSS: 1) perceiving women to use opioids to regulate emotions and 2) gender differences in trauma types. Three themes emerged for providers' perceptions on the development of an OUD/PTSD treatment: 1) barriers to treatment (e.g., chaotic lives, contextual factors, family); 2) treatment facilitators (e.g., trust and external motivations); and 3) desired treatment modifications (e.g., stabilization, early skills in therapy, flexibility in therapy, social supports, safety guidelines, and assistance in identifying an index trauma). Most participants (90.0 %) and providers (93.5 %) preferred working on OUD/PTSD symptoms simultaneously rather than separately.

CONCLUSIONS

Findings demonstrate the need to modify integrated treatments to meet the preferences of providers and women with OUD/PTSS and OUD/PTSD. Treatments should consider therapeutic content, structure, contextual factors, social support, and PTSD severity to enhance uptake and reach.

摘要

简介

女性表现出特定于性别的阿片类药物使用障碍(OUD)和创伤后应激障碍(PTSD)共病风险。专家组呼吁为 OUD/PTSD 女性开发综合治疗方法,但有关此类干预措施的信息仍然有限。

方法

本混合方法研究对 10 名目前或过去患有 OUD 和共患创伤后应激症状(PTSS)的女性和 16 名与这些女性合作的提供者进行了访谈和调查。访谈和调查询问了患者参与者和提供者对 OUD/PTSS 的体验,以及如何最好地设计针对 OUD/PTSD 的综合、以创伤为重点的治疗方法。

结果

患者参与者(90%为白人,90%为母亲,M=45.70)符合严重、终身 OUD 的标准,40%符合暂定 PTSD 诊断。参与者 OUD/PTSS 经历的四个主题出现:1)许多压力源;2)羞耻感;3)使用阿片类药物的多种动机;4)创伤和阿片类药物使用的循环。关于患者参与者对 OUD/PTSD 治疗发展的看法出现了四个主题:1)对 OUD 药物治疗的混合态度;2)治疗障碍(例如,治疗不足和环境因素);3)治疗促进因素(例如,社会支持);4)治疗偏好(例如,以创伤为重点、以性别为重点、包含家庭内容、对团体治疗的矛盾态度)。提供者(M=38.94)主要是白人女性(76.5%)。从他们与患有 OUD/PTSS 的女性合作的经验中出现了两个主题:1)认为女性使用阿片类药物来调节情绪;2)创伤类型的性别差异。提供者对 OUD/PTSD 治疗发展的看法出现了三个主题:1)治疗障碍(例如,混乱的生活、环境因素、家庭);2)治疗促进因素(例如,信任和外部动机);3)治疗修改的期望(例如,稳定、早期治疗技能、治疗灵活性、社会支持、安全准则以及协助确定主要创伤)。大多数参与者(90.0%)和提供者(93.5%)更喜欢同时而不是分别处理 OUD/PTSD 症状。

结论

研究结果表明,需要修改综合治疗方法,以满足 OUD/PTSS 和 OUD/PTSD 女性和提供者的偏好。治疗应考虑治疗内容、结构、环境因素、社会支持和 PTSD 严重程度,以提高接受度和覆盖率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8301/11146521/cd58f2dd1b43/nihms-1992648-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8301/11146521/e7bf3cbc5960/nihms-1992648-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8301/11146521/cd58f2dd1b43/nihms-1992648-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8301/11146521/e7bf3cbc5960/nihms-1992648-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8301/11146521/cd58f2dd1b43/nihms-1992648-f0002.jpg

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