Department of General Surgery, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Department of General Surgery, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
Am J Surg. 2024 Jul;233:136-141. doi: 10.1016/j.amjsurg.2024.03.009. Epub 2024 Mar 11.
The aim of this study was to evaluate cardiovascular disease (CVD) risk modification in patients with optimal weight loss (OWL) versus suboptimal weight loss SWL following MBS.
This was a retrospective analysis. The 10-year risk CVD was estimated before and after one year of surgery using the "Framingham Score".
191 patients were included in our study. Mean baseline Framingham score was 7.2 ± 6.9%. According to the score, 54% of patients were classified as low risk (n = 104), 23% as moderate (n = 43), 20% moderately high (n = 39) and 3% as high risk (n = 5). One year after surgery, 91% of the patients showed reduction of their Framingham score. Mean CVD risk score decreased significantly to 4.1 ± 3.7% when compared to baseline (p-value is < 0.001); 80% of patients classified as low risk (n = 153), 13% as moderate (n = 25), 7% moderately high (n = 13) and 0% as high risk (n = 0).
Weight loss after bariatric surgery reduces CVD risk scores and the magnitude of effect correlates with the degree of weight loss.
本研究旨在评估 MBS 后体重减轻达到理想水平（OWL）与未达到理想水平（SWL）的患者的心血管疾病（CVD）风险改变。
这是一项回顾性分析。使用“弗雷明汉评分”在手术前一年和一年后评估 10 年 CVD 风险。
我们的研究纳入了 191 名患者。基线Framingham 评分的平均值为 7.2 ± 6.9%。根据评分，54%的患者被归类为低危（n = 104），23%为中危（n = 43），20%为中高危（n = 39），3%为高危（n = 5）。手术后一年，91%的患者Framingham 评分降低。与基线相比，平均 CVD 风险评分显著下降至 4.1 ± 3.7%（p 值<0.001）；80%的患者被归类为低危（n = 153），13%为中危（n = 25），7%为中高危（n = 13），0%为高危（n = 0）。
减重手术后体重减轻可降低 CVD 风险评分，且效果的幅度与减重程度相关。
