Miao Sisi, Lu Lin, Si Shengyong, Peng Dandan, Zhong Ya, Li Zhijing, Yu Zhenqiu
The affiliated Hospital of Guizhou Medical University, Department of Hypertension, Guiyang, China.
Chinese Academy of Medical Science and Peking Union Medical College, Peking Union Medical College Hospital, Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Beijing, China.
J Med Biochem. 2024 Jan 25;43(1):19-35. doi: 10.5937/jomb0-43319.
Cardiovascular disease is the leading cause of death in Cushingžs syndrome (CS). Primary bilateral macro-nodular adrenal hyperplasia (PBMAH), is a rare cause of CS that is clinically distinct from the other common types of CS, but cardiac characteristics have been poorly studied.
The clinical data, steroid hormones and echocardiographic variables of 17 patients with PBMAH were collected. Twenty-one CS patients with cortisol-producing adenoma (CPA) were collected as controls. The similarities and differences of clinical and cardiac features between the two groups were compared.
心血管疾病是库欣综合征（CS）的主要死因。原发性双侧大结节性肾上腺增生（PBMAH）是CS的一种罕见病因，在临床上与其他常见类型的CS不同，但心脏特征的研究较少。
收集17例PBMAH患者的临床资料、类固醇激素和超声心动图变量。收集21例产生皮质醇腺瘤（CPA）的CS患者作为对照。比较两组患者临床和心脏特征的异同。
