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高危急性结石性胆囊炎患者经皮影像引导下与腹腔镜胆囊造瘘术的治疗结果:一家地区综合医院的五年经验

Outcomes of Percutaneous Image-Guided and Laparoscopic Cholecystostomies in High-Risk Patients With Acute Calculus Cholecystitis: A Five-Year District General Hospital Experience.

作者信息

Aly Mahmoud S, Jamal Zohaib, Khawaja Zeeshan, Kieu Phuong L, Zafar Nowera, Kanakalingam Divya, Khalil Ahmed

机构信息

Department of Surgery, Wrightington, Wigan and Leigh NHS Foundation Trust, Wigan, GBR.

Department of Otolaryngology, Wrightington, Wigan and Leigh NHS Foundation Trust, Wigan, GBR.

出版信息

Cureus. 2024 Feb 16;16(2):e54313. doi: 10.7759/cureus.54313. eCollection 2024 Feb.

Abstract

Introduction Acute cholecystitis (AC), inflammation of the gall bladder, is one of the most common emergency surgical presentations. In the UK, approximately 15% of the population is estimated to have gallstones, and approximately 20% of them can develop AC. Laparoscopic cholecystectomy (LC) is considered the definitive management of AC. However, cholecystectomy carries a very high risk of morbidity and mortality in high-risk frail patients with multiple comorbidities who are deemed unfit for surgery. Percutaneous cholecystostomy (PC), both image-guided and laparoscopic, is generally acknowledged as an interim treatment measure before definitive management, which is the LC. Materials and methods This is a retrospective study from the Royal Albert Edward Infirmary, a district general hospital (DGH) based in Wigan, UK. The medical records of all the patients who were admitted to the surgical department and underwent PC between January 2017 and December 2022 were analyzed. Patients with previous hepato-pancreato-biliary (HPB) malignancy, who underwent open cholecystostomy, or those with abdominal ascites were excluded from the study. Information was collected regarding the age, gender, American Society of Anaesthesiologists (ASA) grades, success rates of both procedures as temporary or definitive management, duration of hospital stay, 30-day and 1-year mortality after the procedure, timing of the procedure, and long-term complications after the procedure, particularly those related to cholecystostomy tube dislodgment or blockage. Results Twenty-seven patients who underwent PC were divided into two groups: group A, consisting of 10 patients who underwent laparoscopic cholecystostomies, and group B, consisting of 17 patients who had ultrasound (US)-guided cholecystostomies. The mean age of the patients in group A was 66.7 as compared to 75.1 in group B. Most of the patients were in ASA groups III (14) and IV (10). About 74% of patients had procedures done during the day and 26% had PC at night time. The mean hospital stay was 13.5 days. About 55% of patients had planned elective LC as a definitive management. Following the treatment, two patients died within 30 days, and eight patients passed away within a year. About 40% of the patients had complications related to the tube dislodgment and blockage. Conclusion This study concludes that PC, using both laparoscopic and US-guided techniques, can serve as an interim as well as a definitive measure, particularly in patients who are at high risk for anesthesia and the procedure itself and have multiple comorbidities.

摘要

引言

急性胆囊炎(AC),即胆囊的炎症,是最常见的急诊外科病症之一。在英国,估计约15%的人口患有胆结石,其中约20%会发展为急性胆囊炎。腹腔镜胆囊切除术(LC)被认为是急性胆囊炎的确定性治疗方法。然而,对于患有多种合并症、被认为不适合手术的高危体弱患者,胆囊切除术具有非常高的发病和死亡风险。经皮胆囊造瘘术(PC),包括影像引导和腹腔镜引导的,通常被认为是在确定性治疗(即LC)之前的一种临时治疗措施。

材料与方法

这是一项来自英国维根的地区综合医院皇家阿尔伯特·爱德华医院的回顾性研究。分析了2017年1月至2022年12月期间所有入住外科并接受经皮胆囊造瘘术的患者的病历。排除既往有肝胰胆(HPB)恶性肿瘤、接受过开腹胆囊造瘘术或有腹腔积液的患者。收集了有关年龄、性别、美国麻醉医师协会(ASA)分级、作为临时或确定性治疗的两种手术的成功率、住院时间、术后30天和1年死亡率、手术时间以及术后长期并发症的信息,特别是与胆囊造瘘管移位或堵塞相关的并发症。

结果

27例接受经皮胆囊造瘘术的患者分为两组:A组,由10例接受腹腔镜胆囊造瘘术的患者组成;B组,由17例接受超声(US)引导下胆囊造瘘术的患者组成。A组患者的平均年龄为66.7岁,而B组为75.1岁。大多数患者属于ASA III组(14例)和IV组(10例)。约74%的患者在白天进行手术,26%的患者在夜间进行经皮胆囊造瘘术。平均住院时间为13.5天。约55%的患者计划择期进行腹腔镜胆囊切除术作为确定性治疗。治疗后,2例患者在30天内死亡,8例患者在一年内死亡。约40%的患者出现与导管移位和堵塞相关的并发症。

结论

本研究得出结论,使用腹腔镜和超声引导技术的经皮胆囊造瘘术既可以作为一种临时措施,也可以作为一种确定性措施,特别是对于麻醉和手术本身风险高且有多种合并症的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74b1/10944319/94662f0eeed9/cureus-0016-00000054313-i01.jpg

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