Nicoletti F, Raffaele R, Falsaperla A
Riv Neurol. 1979 May-Jun;49(3):219-30.
Some interpretative hypotheses of the most important symptoms of Parkinson's disease are formulated, on the ground of acquired neurohistopathologic elements and in the light of new observations of experimental neuro-physiology. The possible role of the inferior olivary body in the genesis of parkinsonian tremor is pointed out. The psycho-behavioural disorders and among these the severe weakness of pulsional control and the scanty elaboration of the affective-emotional motivation would be in relation, according to the Authors, to the involvement of the pallido-habenular pathways and the habenuloreticular midbrain outflow (limbic midbrain area).
基于获得性神经组织病理学因素并结合实验神经生理学的新观察结果，提出了关于帕金森病最重要症状的一些解释性假说。指出了下橄榄体在帕金森震颤发生过程中可能发挥的作用。作者认为，心理行为障碍，尤其是冲动控制严重不足和情感 - 情绪动机缺乏，与苍白球 - 缰核通路及缰核 - 网状中脑传出通路（边缘中脑区域）受累有关。
