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Targeting bone marrow mechanosensation in myelofibrosis.

作者信息

Vinchi Francesca

机构信息

Iron Research Laboratory Lindsley F. Kimball Research Institute, New York Blood Center New York New York USA.

Department of Pathology and Laboratory Medicine Weill Cornell Medicine New York New York USA.

出版信息

Hemasphere. 2024 Mar 17;8(3):e46. doi: 10.1002/hem3.46. eCollection 2024 Mar.

DOI:10.1002/hem3.46
PMID:38501049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10945038/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e32/10945038/d11d29b24b24/HEM3-8-e46-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e32/10945038/d11d29b24b24/HEM3-8-e46-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e32/10945038/d11d29b24b24/HEM3-8-e46-g001.jpg

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本文引用的文献

1
Newly identified roles for PIEZO1 mechanosensor in controlling normal megakaryocyte development and in primary myelofibrosis.PIEZO1机械传感器在控制正常巨核细胞发育和原发性骨髓纤维化中的新发现作用。
Am J Hematol. 2024 Mar;99(3):336-349. doi: 10.1002/ajh.27184. Epub 2024 Jan 2.
2
Piezo1 initiates platelet hyperreactivity and accelerates thrombosis in hypertension.Piezo1 引发血小板反应过度，并加速高血压患者的血栓形成。
J Thromb Haemost. 2021 Dec;19(12):3113-3125. doi: 10.1111/jth.15504. Epub 2021 Oct 8.
3
Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing.
机械激活的离子通道 Piezo1 调节巨噬细胞极化和刚性感知。
Nat Commun. 2021 May 31;12(1):3256. doi: 10.1038/s41467-021-23482-5.
4
PIEZO1 activation delays erythroid differentiation of normal and hereditary xerocytosis-derived human progenitor cells.机械敏感离子通道蛋白 1（PIEZO1）的激活可延迟正常和遗传性先天性非球形细胞性溶血性贫血（hereditary xerocytosis）衍生的人祖细胞的红系分化。
Haematologica. 2020 Mar;105(3):610-622. doi: 10.3324/haematol.2019.218503. Epub 2019 Aug 14.
5
A new path to platelet production through matrix sensing.通过基质感知实现血小板生成的新途径。
Haematologica. 2017 Jul;102(7):1150-1160. doi: 10.3324/haematol.2016.161562. Epub 2017 Apr 14.
6
Bone marrow fibrosis in myelofibrosis: pathogenesis, prognosis and targeted strategies.骨髓纤维化症中的骨髓纤维化：发病机制、预后及靶向治疗策略
Haematologica. 2016 Jun;101(6):660-71. doi: 10.3324/haematol.2015.141283.
7
Piezo1 links mechanical forces to red blood cell volume.Piezo1将机械力与红细胞体积联系起来。
Elife. 2015 May 22;4:e07370. doi: 10.7554/eLife.07370.
8
Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies.用于体外生成血小板和巨核细胞生成病理学建模的可编程3D丝质骨髓微环境
Blood. 2015 Apr 2;125(14):2254-64. doi: 10.1182/blood-2014-08-595561. Epub 2015 Jan 9.