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社交网络策略(SNS)在艾滋病病毒检测中的应用:坦桑尼亚发现未确诊艾滋病病毒感染者的新方法。

Social network strategy (SNS) for HIV testing: a new approach for identifying individuals with undiagnosed HIV infection in Tanzania.

机构信息

United States Centers for Disease Control and Prevention, Dar es Salaam, Division of Global HIV and TB, Dar es Salaam, Tanzania.

United States Centers for Disease Control and Prevention, Division of Global HIV and TB, Atlanta, Georgia, USA.

出版信息

AIDS Care. 2024 Jul;36(sup1):201-210. doi: 10.1080/09540121.2024.2307383. Epub 2024 Mar 19.

Abstract

Social network strategy (SNS) testing uses network connections to refer individuals at high risk to HIV testing services (HTS). In Tanzania, SNS testing is offered in communities and health facilities. In communities, SNS testing targets key and vulnerable populations (KVP), while in health facilities it complements index testing by reaching unelicited index contacts. Routine data were used to assess performance and trends over time in PEPFAR-supported sites between October 2021 and March 2023. Key indicators included SNS social contacts tested, and new HIV-positives individuals identified. Descriptive and statistical analysis were conducted. Univariable and multivariable analysis were applied, and variables with -values <0.2 at univariable analysis were considered for multivariable analysis. Overall, 121,739 SNS contacts were tested, and 7731 (6.4%) previously undiagnosed individuals living with HIV were identified. Tested contacts and identified HIV-positives were mostly aged ≥15 years (>99.7%) and females (80.6% of tests, 79.4% of HIV-positives). Most SNS contacts were tested (78,363; 64.7%) and diagnosed (6376; 82.5%) in communities. SNS tests and HIV-positives grew 11.5 and 6.1-fold respectively, from October-December 2021 to January-March 2023, with majority of clients reached in communities vs. facilities (78,763 vs. 42,976). These results indicate that SNS testing is a promising HIV case-finding approach in Tanzania.

摘要

社交网络策略(SNS)测试利用网络连接将高危个体转介到艾滋病毒检测服务(HTS)。坦桑尼亚在社区和卫生机构提供 SNS 测试。在社区中,SNS 测试针对关键和脆弱人群(KVP),而在卫生机构中,它通过接触未被招募的索引接触者来补充索引测试。使用常规数据评估 2021 年 10 月至 2023 年 3 月期间 PEPFAR 支持的地点的性能和随时间的趋势。关键指标包括 SNS 测试的社交联系人数量和新发现的 HIV 阳性个体数量。进行了描述性和统计分析。进行了单变量和多变量分析,并对单变量分析中 P 值<0.2 的变量进行了多变量分析。总体而言,共测试了 121739 名 SNS 联系人,发现了 7731 名(6.4%)以前未被诊断的 HIV 感染者。接受测试的联系人以及发现的 HIV 阳性者主要年龄≥15 岁(>99.7%)和女性(80.6%的测试,79.4%的 HIV 阳性者)。大多数 SNS 联系人(78363 人;64.7%)在社区接受了测试(6376 人;82.5%)。从 2021 年 10 月至 12 月至 2023 年 1 月至 3 月,SNS 测试和 HIV 阳性分别增长了 11.5 倍和 6.1 倍,大部分客户是在社区而不是在机构中接触到的(78763 人对 42976 人)。这些结果表明,SNS 测试是坦桑尼亚一种有前途的 HIV 病例发现方法。

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