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血管外科医生在经导管主动脉瓣植入术中的作用。

The role of the vascular surgeon in transcatheter aortic valve implantation.

作者信息

Gallitto Enrico, Faggioli Gianluca, Saia Francesco, Palmerini Tullio, Pini Rodolfo, Bruno Antonio Giulio, Feroldi Francesca Maria, Alaidroos Moad, Ghetti Gabriele, Taglieri Nevio, Caputo Stefania, Donati Francesco, Marrozzini Cinzia, Gargiulo Mauro

机构信息

Vascular Surgery, Department of Experimental, Diagnostic and Specialty Medicine, IRCCS Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

Division of Interventional Cardiology, IRCCS Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

出版信息

Vascular. 2025 Aug;33(4):861-869. doi: 10.1177/17085381241237844. Epub 2024 Mar 19.

DOI:10.1177/17085381241237844
PMID:38504140
Abstract

BackgroundTranscatheter aortic valve implantation (TAVI) has become the standard treatment for severe aortic valve stenosis in patients at increased surgical risk. Percutaneous transfemoral (TF) is the access of choice due to its reduced invasiveness and perioperative morbidity/mortality compared with the trans-axillary, aortic, and apical routes. On the other hand, vascular access complications (VACs) of the TF access are associated with prolonged hospitalization, 30-day, and 1-year mortality. In addition, the concomitance of peripheral arterial disease may require associated endovascular management. A multidisciplinary team with Interventional Cardiologists and Vascular Surgeons may minimize the rate of VACs in patients with challenging femoral-iliac access or concomitant disease of other vascular districts, thus optimizing the outcome of TF-TAVI. The aim of this study was to evaluate the role of Vascular Surgeons in TF TAVI procedures.MethodsWe conducted a retrospective single-center review of all TF-TAVI procedures assisted by Vascular Surgeons between January 2016 and December 2020 in a high-volume tertiary hospital. Pre, intra, and postoperative data were analyzed by a dedicated group of Interventional Cardiologists and Vascular Surgeons. VACs were defined according with the Valve Academic Research Consortium (VARC) three guidelines. The outcomes of TF-TAVI procedures with Vascular Surgeons involvement were assessed as study's endpoints.ResultsOverall, 937 TAVI procedures were performed with a TF approach ranging between 78% (2016) and 98% (2020). Vascular Surgeons were involved in 67 (7%) procedures with the following indications: concomitant abdominal aortic aneurysm (EVAR + TAVI) - 3 (4%), carotid stenosis (TAVI + CAS) - 2 (3%), hostile femoral/iliac access, or VACs - 62 (93%). Balloon angioplasty of iliac artery pre-TAVI implantation was performed in 51 cases (conventional PTA: 38/51%-75%; conventional PTA + intravascular lithotripsy: 13/51%-25%; stenting: 5/51%-10%). TAVI procedure was successfully completed by percutaneous TF approach in all 62 cases with challenging femoral/iliac access. VACs necessitating interventions were 18/937 (2%) cases, localized to the common femoral or common/external iliac artery in 15/18 (83%) and 3/18 (17%) cases, respectively. They were managed by surgical or endovascular maneuvers in 3/18 (17%) and 15/18 (83%) cases, respectively. Fifteen/18 (83%) VACs were treated during the index procedure. There was no procedure-related mortality or 30-day readmission.ConclusionIn our experience, Vascular Surgeon assistance in TAVI procedures was not infrequent and allowed safe and effective device introduction through challenging TF access. Similarly, the concomitant significant disease of other vascular districts could be safely addressed, potentially reducing postoperative related mortality and morbidity. The implementation of multidisciplinary team with interventional cardiologists and vascular surgeons should be encouraged whenever possible.

摘要

背景

经导管主动脉瓣植入术(TAVI)已成为手术风险增加的严重主动脉瓣狭窄患者的标准治疗方法。与经腋动脉、主动脉和心尖途径相比,经皮股动脉(TF)途径因其侵入性较小以及围手术期发病率/死亡率较低,成为首选的入路方式。另一方面,TF入路的血管通路并发症(VACs)与住院时间延长、30天和1年死亡率相关。此外,外周动脉疾病的并存可能需要相关的血管内治疗。由介入心脏病学家和血管外科医生组成的多学科团队可以将具有挑战性的股-髂入路或其他血管区域并存疾病患者的VACs发生率降至最低,从而优化TF-TAVI的治疗效果。本研究的目的是评估血管外科医生在TF-TAVI手术中的作用。

方法

我们对2016年1月至2020年12月期间在一家大型三级医院由血管外科医生协助进行的所有TF-TAVI手术进行了回顾性单中心研究。术前、术中和术后数据由一组专门的介入心脏病学家和血管外科医生进行分析。VACs根据瓣膜学术研究联盟(VARC)三项指南进行定义。血管外科医生参与的TF-TAVI手术结果被评估为研究终点。

结果

总体而言,共进行了937例TAVI手术,采用TF入路的比例在78%(2016年)至98%(2020年)之间。血管外科医生参与了67例(7%)手术,其适应症如下:并存腹主动脉瘤(EVAR + TAVI)-3例(4%),颈动脉狭窄(TAVI + CAS)-2例(3%),股/髂入路困难或VACs-62例(93%)。51例患者在TAVI植入术前进行了髂动脉球囊血管成形术(传统PTA:38/51%-75%;传统PTA + 血管内碎石术:13/51%-25%;支架置入术:5/51%-10%)。所有62例股/髂入路困难的患者均通过经皮TF入路成功完成了TAVI手术。需要干预的VACs为18/937例(2%),分别有15/18例(83%)和3/18例(17%)局限于股总动脉或髂总/外动脉。分别有3/18例(17%)和15/18例(83%)通过手术或血管内操作进行处理。15/18例(83%)VACs在索引手术期间得到治疗。没有与手术相关的死亡或30天再入院情况。

结论

根据我们的经验,血管外科医生在TAVI手术中的协助并不罕见,并且能够通过具有挑战性的TF入路安全有效地植入器械。同样,其他血管区域的并存重大疾病也能够得到安全处理,有可能降低术后相关死亡率和发病率。应尽可能鼓励组建由介入心脏病学家和血管外科医生组成的多学科团队。

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