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妊娠合并低钾性周期性麻痹:一例报告

Hypokalemic Periodic Paralysis in Pregnancy: A Case Report.

作者信息

Muhammad Aliyu Rabi'at, Suleiman Bawa Umma, Atta Abubakar Sani, Shehu Abdullahi Aisha, Maiwada Suleiman Hafsat, Zulaihatu Sarkin-Pawa, Yunusa Yusuf Rahmatu, Adogie Abdul Muhammad

机构信息

Department of Obstetrics and Gynaecology, Ahmadu Bello University, Zaria, Nigeria.

Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.

出版信息

Niger Med J. 2022 Apr 25;62(2):92-95. eCollection 2021 Mar-Apr.

Abstract

BACKGROUND

Myopathy is a disorder of skeletal muscles and has a rare occurrence in pregnancy. It may present with numbness/weakness. The occurrence of isolated weakness involving all the limbs is alarming to the patient and the diagnosis can be challenging to the Obstetrician. We present a case of hypokalaemic paralysis in pregnancy.

CASE REPORT

A 32-year-old grand multipara presented at 31 weeks gestation with numbness in all limbs for nine days and one-day history of weakness in all limbs. She had a similar episode in her last pregnancy with complete resolution by the end of puerperium. On examination, she was conscious with a Glasgow Coma Scale score was 15/15, had no signs of meningeal irritation, and no cranial nerve palsy. She had normal muscle bulk; the power of 4/5 in both upper limbs and 3/5 in both lower limbs. There was no clearly defined sensory level. Planter reflex was flexor symmetrically. A review of other systems was unremarkable. Her PCV was 35% and random blood glucose was 4.2mmol/l. Serum biochemistry showed severe hypokalaemia of 1.8mmol/l with normal levels of sodium and chloride. Urinary potassium level was normal. She had parenteral correction of potassium with complete resolution of weakness, and she was maintained on oral potassium supplements. She had an uneventful delivery at 37 weeks gestation.

CONCLUSION

Measuring the serum level of potassium should be part of the initial workup when evaluating pregnant women presenting with muscle weakness. Multidisciplinary management leads to early diagnosis, prompt management, and a good prognosis.

摘要

背景

肌病是一种骨骼肌疾病,在妊娠期罕见。其症状可能包括麻木/无力。孤立性四肢无力的情况对患者来说令人担忧,且诊断对产科医生而言可能具有挑战性。我们报告一例妊娠期低钾性麻痹病例。

病例报告

一名32岁的经产妇在妊娠31周时出现四肢麻木9天,四肢无力1天。她上一次怀孕时曾有类似发作,产褥期末完全缓解。检查时,她意识清醒,格拉斯哥昏迷量表评分为15/15,无脑膜刺激征,无颅神经麻痹。她的肌肉量正常;双上肢肌力为4/5,双下肢肌力为3/5。没有明确的感觉平面。跖反射对称呈屈曲型。其他系统检查无异常。她的红细胞压积为35%,随机血糖为4.2mmol/l。血清生化检查显示严重低钾血症,血钾为1.8mmol/l,钠和氯水平正常。尿钾水平正常。她接受了静脉补钾,无力症状完全缓解,之后维持口服补钾治疗。她在妊娠37周时顺利分娩。

结论

在评估出现肌无力的孕妇时,测定血清钾水平应作为初始检查的一部分。多学科管理可实现早期诊断、及时治疗并获得良好预后。

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