Pilarz Mary S, Walker Sarah B, Rowland Matthew J
Division of Critical Care, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Department of Anesthesia, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
J Vasc Access. 2025 Mar;26(2):641-645. doi: 10.1177/11297298241236405. Epub 2024 Mar 20.
Peripheral arterial catheters (PACs), and their associated complications, are common in the pediatric intensive care unit (PICU). Accidental catheter displacement and non-functional PACs are the most common complications, and this may be related to inadequate catheter securement. There is mixed guidance on the best way to secure PACs to prevent complications. The authors hypothesized that sutures would not be associated with a decreased risk of malfunction or accidental removal.
This was a single center retrospective cohort study at a quaternary-care PICU. PICU patients with a peripheral arterial catheter placed in the PICU from 7/2020 to 1/2023 were included. The primary outcome was unplanned PAC removal. A univariate and multivariate Cox proportional hazards regression analysis was performed, using patient weight, sedation, paralytic, and role of the proceduralist as covariates. The secondary outcome was survival probability. A log-rank test was used to compare survival curves.
Of 761 PACs that met inclusion criteria in 437 unique patients, 599 were sutured (78.7%) and 162 were un-sutured (21.3%). In 257 cases (33.8%), the PAC had an unplanned removal. Among all PACs, the median duration of PAC placement was 5.3 days (IQR 2.1-10.5 days). There was an unplanned removal rate of 42.2% (68) in the un-sutured group and 31.4% (188) in the sutured group ( < 0.001). In multivariable analysis, sutured PACs were also associated with a lower rate of unplanned removal (hazard ratio, 0.59; 95% CI, 0.44-0.78). Use of continuous sedation was also associated with an increased risk of unplanned removal of PACs (hazard ratio, 1.54; 95% CI, 1.10-2.16). There was a 50% survival probability at 13.3 days for un-sutured PACs and 23.7 days for sutured PACs.
Suturing is associated with fewer unplanned removals and longer catheter survival, compared to un-sutured PACs in pediatric patients.
外周动脉导管(PACs)及其相关并发症在儿科重症监护病房(PICU)中很常见。意外导管移位和无功能的PACs是最常见的并发症,这可能与导管固定不充分有关。关于固定PACs以预防并发症的最佳方法,目前的指导意见并不统一。作者推测,缝线固定与降低故障或意外拔除风险无关。
这是一项在四级医疗PICU进行的单中心回顾性队列研究。纳入2020年7月至2023年1月在PICU放置外周动脉导管的PICU患者。主要结局是计划外拔除PACs。进行单变量和多变量Cox比例风险回归分析,将患者体重、镇静、麻痹和操作医生的角色作为协变量。次要结局是生存概率。使用对数秩检验比较生存曲线。
在437例符合纳入标准的独特患者中的761根PACs中,599根采用缝线固定(78.7%),162根未采用缝线固定(21.3%)。在257例(33.8%)病例中,PACs出现了计划外拔除。在所有PACs中,PACs放置的中位持续时间为5.3天(IQR 2.1 - 10.5天)。未采用缝线固定组的计划外拔除率为42.2%(68例),采用缝线固定组为31.4%(188例)(<0.001)。在多变量分析中,采用缝线固定的PACs计划外拔除率也较低(风险比,0.59;95%CI,0.44 - 0.78)。使用持续镇静也与PACs计划外拔除风险增加相关(风险比,1.54;95%CI,1.10 - 2.16)。未采用缝线固定的PACs在13.3天时生存概率为50%,采用缝线固定的PACs为23.7天。
与儿科患者中未采用缝线固定的PACs相比,缝线固定与更少的计划外拔除和更长的导管存活时间相关。