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妊娠时急性颅内紧急情况的处理。

Management of an acute intracranial emergency in pregnancy.

机构信息

Obstetrics and Gynaecology, Medisch Spectrum Twente, Enschede, The Netherlands.

Neurosurgery, Medisch Spectrum Twente, Enschede, The Netherlands.

出版信息

BMJ Case Rep. 2024 Mar 19;17(3):e258066. doi: 10.1136/bcr-2023-258066.

DOI:10.1136/bcr-2023-258066
PMID:38508596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10953304/
Abstract

We report a case of a mid-20s primigravida at 37 weeks' gestation who presented with severe headache and acute neurological deterioration. The CT brain scan showed hydrocephalus caused by a colloid cyst in the third ventricle. The patient underwent emergency placement of an external ventricular drain for decompression of acute hydrocephalus. Four hours later, labour commenced spontaneously, and in view of her neurological status, a decision was taken to perform a caesarean section under general anaesthetics. Four days postpartum, the patient underwent an endoscopic removal of the cyst. Intracranial emergencies during pregnancy are rare and challenging to manage. The mortality rate can be significant. Diagnostic and surgical intervention should not be delayed because of pregnancy. An individualised treatment approach is required with multidisciplinary input. The collaborative efforts of our multidisciplinary team resulted in prompt diagnosis and surgical treatment in this case that resulted in both a healthy mother and child.

摘要

我们报告了一例 20 多岁的初产妇,妊娠 37 周,出现严重头痛和急性神经功能恶化。脑部 CT 扫描显示第三脑室的胶样囊肿引起脑积水。患者行紧急脑室外引流术以缓解急性脑积水。4 小时后,自然分娩开始,鉴于她的神经状态,决定在全身麻醉下进行剖宫产。产后 4 天,患者行内镜下囊肿切除术。怀孕期间的颅内急症罕见且难以处理。死亡率可能很高。不应因怀孕而延迟诊断和手术干预。需要采用个体化治疗方法并多学科参与。我们的多学科团队的协作努力在本例中实现了快速诊断和手术治疗,母婴均健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0d/10953304/449eb00d834b/bcr-2023-258066f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0d/10953304/026d71cf0e09/bcr-2023-258066f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0d/10953304/81f1d7ddf46a/bcr-2023-258066f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0d/10953304/449eb00d834b/bcr-2023-258066f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0d/10953304/026d71cf0e09/bcr-2023-258066f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0d/10953304/81f1d7ddf46a/bcr-2023-258066f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0d/10953304/449eb00d834b/bcr-2023-258066f03.jpg

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BMJ Case Rep. 2024 Mar 19;17(3):e258066. doi: 10.1136/bcr-2023-258066.
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本文引用的文献

1
Risk of adverse fetal outcomes following nonobstetric surgery during gestation: a nationwide population-based analysis.妊娠期间非产科手术与不良胎儿结局风险:一项全国范围内基于人群的分析。
BMC Pregnancy Childbirth. 2022 May 13;22(1):406. doi: 10.1186/s12884-022-04732-w.
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Acute Intracranial Hypertension During Pregnancy: Special Considerations and Management Adjustments.妊娠期急性颅内高压:特殊考虑和管理调整。
Neurocrit Care. 2022 Feb;36(1):302-316. doi: 10.1007/s12028-021-01333-x. Epub 2021 Sep 7.
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Intracranial emergencies during pregnancy requiring urgent neurosurgical treatment.
妊娠期需要紧急神经外科治疗的颅内急症。
Clin Neurol Neurosurg. 2020 Aug;195:105905. doi: 10.1016/j.clineuro.2020.105905. Epub 2020 May 12.
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Obstetric and non-obstetric surgery during pregnancy: A 20-year Danish population-based prevalence study.妊娠期间的产科和非产科手术:一项丹麦基于人群的 20 年患病率研究。
BMJ Open. 2019 May 19;9(5):e028136. doi: 10.1136/bmjopen-2018-028136.
5
Spinal anesthesia performed for cesarean delivery after external ventricular drain placement in a parturient with symptomatology from an intracranial mass.一名患有颅内肿块症状的产妇在放置体外脑室引流管后行剖宫产术时实施了脊髓麻醉。
Int J Obstet Anesth. 2019 Feb;37:122-125. doi: 10.1016/j.ijoa.2018.08.010. Epub 2018 Sep 6.
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Nonobstetric Surgery During Pregnancy.孕期非产科手术。
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Headache and pregnancy: a systematic review.头痛与妊娠:一项系统综述
J Headache Pain. 2017 Oct 19;18(1):106. doi: 10.1186/s10194-017-0816-0.
8
The Risk of Adverse Pregnancy Outcomes Following Nonobstetric Surgery During Pregnancy: Estimates From a Retrospective Cohort Study of 6.5 Million Pregnancies.妊娠期间非产科手术与不良妊娠结局风险:一项 650 万例妊娠回顾性队列研究的估计。
Ann Surg. 2017 Aug;266(2):260-266. doi: 10.1097/SLA.0000000000001976.
9
Surgical management of colloid cyst of the third ventricle.第三脑室胶样囊肿的手术治疗
Acta Neurol Scand. 2017 Apr;135(4):484-487. doi: 10.1111/ane.12632. Epub 2016 Jun 27.
10
Natural history of colloid cysts of the third ventricle.第三脑室胶样囊肿的自然史。
J Neurosurg. 2016 Dec;125(6):1420-1430. doi: 10.3171/2015.11.JNS151396. Epub 2016 Mar 11.