Loo Germaine, Puar Troy, Foo Roger, Ong Tiong Kiam, Wang Tzung-Dau, Nguyen Quang Ngoc, Chin Chee Tang, Chin Calvin W L
Department of Cardiology, National Heart Centre Singapore.
Department of Endocrinology, Changi General Hospital.
J Hypertens. 2024 Sep 1;42(9):1482-1489. doi: 10.1097/HJH.0000000000003706. Epub 2024 Mar 12.
Hypertension remains the leading modifiable risk factor for cardiovascular disease worldwide. Over the past 30 years, the prevalence of hypertension has been increasing in East and Southeast Asia to a greater extent as compared with other Western countries. Asians with hypertension have unique characteristics. This can be attributed to increased impact of obesity on Asians with hypertension, excessive salt intake and increased salt sensitivity, loss of diurnal rhythm in blood pressure and primary aldosteronism. The impact of hypertension on cardiovascular (particularly strokes) and chronic kidney disease is greater in Asians. These unique characteristics underpinned by the diverse socioeconomic backgrounds pose its own challenges in the diagnosis and management of hypertension in Asia.
高血压仍然是全球心血管疾病的首要可改变风险因素。在过去30年里,与其他西方国家相比,东亚和东南亚地区高血压的患病率上升幅度更大。亚洲高血压患者具有独特的特征。这可归因于肥胖对亚洲高血压患者的影响增加、盐摄入量过多和盐敏感性增加、血压昼夜节律消失以及原发性醛固酮增多症。高血压对亚洲人心血管疾病(尤其是中风)和慢性肾脏病的影响更大。这些独特特征在不同的社会经济背景下,给亚洲高血压的诊断和管理带来了挑战。