Suppr超能文献

一项具有长期随访的随机对照试验:颈椎前路椎间盘切除术后(ACD)或颈椎前路椎间盘切除并人工关节置换术后(ACDA)颈椎活动度质量。

A randomized controlled trial with extended long-term follow-up: Quality of cervical spine motion after anterior cervical discectomy (ACD) or anterior cervical discectomy with arthroplasty (ACDA).

作者信息

Schuermans Valérie N E, Smeets Anouk Y J M, Curfs Inez, van Santbrink Henk, Boselie Toon F M

机构信息

Dept. of Neurosurgery, Maastricht University Medical Center, Maastricht, the Netherlands.

Dept. of Neurosurgery, Zuyderland Medical Center, Heerlen, the Netherlands.

出版信息

Brain Spine. 2023 Dec 14;4:102726. doi: 10.1016/j.bas.2023.102726. eCollection 2024.

Abstract

INTRODUCTION

In previous research, a consistent sequence of segmental contributions during dynamic extension X-rays of the cervical spine was observed in 80-90% of healthy participants.

RESEARCH QUESTION

To investigate whether this previously defined 'normal' sequence of segmental contributions was present in patients who underwent anterior cervical discectomy with arthroplasty (ACDA) or anterior cervical discectomy (ACD).

MATERIALS & METHODS: A randomized controlled trial with extended follow-up was conducted. Patients with single level cervical degenerative radiculopathy with a surgical indication were included and randomized. Dynamic X-ray recordings were made before surgery, one-year post-operative, and at long term follow-up.

RESULTS

A total of 27 patients were included, three in an ACDA pilot group and 24 were randomized to receive ACDA (N = 12) or ACD (N = 12). A total of 20 patients were available for follow-up. Preoperatively, 16.7% of patients in the ACDA group and 58.3% of patients in the ACD group showed a normal sequence. One-year post-operative, 66.7% showed a normal sequence in the ACDA group versus 30.0% in the ACD group (p = 0.036). After an average of 11-years follow-up, a normal sequence was observed in 9.1% of patients in the ACDA group and in none of the patients in the ACD group (p = 0.588).

DISCUSSION & CONCLUSION: These findings suggest that while ACDA can restore and preserve a normal sequence of segmental contributions in the short term, this effect is not maintained in the long term. Throughout the process of ageing, not only the quantity, but also the quality of motion changes.

摘要

引言

在先前的研究中,80-90%的健康参与者在颈椎动态伸展X射线下观察到节段性贡献的一致序列。

研究问题

调查在接受颈椎前路椎间盘切除伴人工关节置换术(ACDA)或颈椎前路椎间盘切除术(ACD)的患者中是否存在先前定义的节段性贡献“正常”序列。

材料与方法

进行了一项延长随访的随机对照试验。纳入有手术指征的单节段颈椎退行性神经根病患者并进行随机分组。在手术前、术后一年和长期随访时进行动态X射线记录。

结果

共纳入27例患者,3例在ACDA试验组,24例随机接受ACDA(n = 12)或ACD(n = 12)。共有20例患者可供随访。术前,ACDA组16.7%的患者和ACD组58.3%的患者显示正常序列。术后一年,ACDA组66.7%的患者显示正常序列,而ACD组为30.0%(p = 0.036)。平均随访11年后,ACDA组9.1%的患者观察到正常序列,ACD组无一例患者观察到正常序列(p = 0.588)。

讨论与结论

这些发现表明,虽然ACDA在短期内可以恢复并保留节段性贡献的正常序列,但这种效果在长期内无法维持。在整个衰老过程中,不仅运动的量,而且运动的质量都会发生变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/613f/10951699/975ea6e57a31/gr1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验