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胸壁促纤维增生性黑色素瘤：诊断难题

Desmoplastic Melanoma of the Chest Wall: a Diagnostic Dilemma.

作者信息

Khan Adil Aziz, Zaheer Sufian, Gulati Parth, Ahuja Sana

机构信息

Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

Department of Radiology, Hamdard Institute of Medical Sciences and Research, New Delhi, India.

出版信息

Indian J Surg Oncol. 2024 Mar;15(1):164-167. doi: 10.1007/s13193-023-01851-4. Epub 2023 Nov 23.

DOI:10.1007/s13193-023-01851-4
PMID:38511025
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10948693/
Abstract

Desmoplastic melanoma is an extremely rare subtype of malignant melanoma comprising only 1% of all the cutaneous melanomas. Being amelanotic and owing to its histopathological features of spindle cells lying in a collagenized stroma, it is often misdiagnosed as a dermatofibroma or scar tissue. The present case study describes a case of desmoplastic melanoma of the chest wall where the final diagnosis could be arrived at only after an extensive immunohistochemical panel to exclude other spindle cell proliferations.

摘要

促纤维增生性黑色素瘤是恶性黑色素瘤中一种极其罕见的亚型，仅占所有皮肤黑色素瘤的1%。由于其无黑色素且具有梭形细胞位于胶原化基质中的组织病理学特征，它常被误诊为皮肤纤维瘤或瘢痕组织。本病例研究描述了一例胸壁促纤维增生性黑色素瘤，只有在进行广泛的免疫组织化学检测以排除其他梭形细胞增殖后才能得出最终诊断。

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