Department of Orthopaedics, Golden Jubilee University National Hospital, Agamemnon Street, Clydebank, Glasgow, G81 4DY, UK.
Arch Orthop Trauma Surg. 2024 May;144(5):2239-2247. doi: 10.1007/s00402-024-05246-0. Epub 2024 Mar 21.
A significant proportion of patients remain dissatisfied following total knee arthroplasty (TKA) surgery. Reasons for this are unclear. Contemporary implants seek to mirror innate anatomy. Such innovations are necessarily subject to scrutiny to validate their use. The Zimmer-Biomet Persona® Personalized Knee system is such an anatomic TKA. This work seeks to establish medium term survival data and patient reported outcomes for this implant.
This was a cohort study of prospectively collected data on all patients undergoing Persona TKA at our institution. Patients were managed using a standardised protocol for intra- and post-operative care. Survivorship data were collected using our National Joint Registry and corroborated with local data. Range of motion, Oxford Knee Score (OKS) and patient satisfaction were recorded at six weeks and one year post-operatively. Hip-knee-ankle radiographs were used to record pre- and post-operative alignment.
Data were collected for 749 knees in 679 patients. Overall survivorship was 99.0% at a mean 5.35 years, with seven patients undergoing revision surgery during the study period. Significant improvements in the OKS (mean 20.7 points) and range of motion were observed (mean 104.6° at one year). 94.9% of patients were satisfied at one year. Mean correction was to a mechanical femoro-tibial angle of 0.8° varus.
We demonstrate excellent medium term survival of the Persona TKA in this large cohort, coupled with improvements in patient reported outcomes, range of motion and patient satisfaction at one year which compare favourably to other implants.
全膝关节置换术（TKA）后仍有相当一部分患者不满意。原因尚不清楚。现代植入物试图模仿先天解剖结构。此类创新必然需要受到审查，以验证其使用。 Zimmer-Biomet Persona®个性化膝关节系统就是这样一种解剖型 TKA。这项工作旨在为该植入物建立中期生存数据和患者报告的结果。
这是一项对我院所有接受 Persona TKA 患者前瞻性收集数据的队列研究。患者采用标准化的围手术期管理方案进行治疗。生存数据通过我们的国家关节登记处收集，并与当地数据相核实。术后六周和一年时，记录了关节活动度、牛津膝关节评分（OKS）和患者满意度。术前和术后髋关节-膝关节-踝关节 X 线片用于记录术前和术后的对线。
共收集了 679 名患者的 749 膝数据。平均 5.35 年的总体生存率为 99.0%，研究期间有 7 例患者接受了翻修手术。OKS（平均 20.7 分）和关节活动度显著改善（平均 1 年时为 104.6°）。1 年后，94.9%的患者满意。平均矫正为机械性股骨-胫骨角 0.8° 内翻。
我们在这个大型队列中证明了 Persona TKA 的优异中期生存率，同时在 1 年内患者报告的结果、关节活动度和患者满意度也得到了改善，与其他植入物相比具有优势。
