Chabaud R, Guenoun M, Taddei J P, Guillou J
Sem Hop. 1979;55(9-10):465-9.
The authors have experimented tiapride in 37 cases of abnormal movements and 20 cases of shaking anxio depresive origin. The best indication of tiapride corresponds to lingual buccal an facial dyskinesia caused by neuroleptics and senile trembling increased by alcoholism. On the other hand its anxiolytic and anti shaking properties are more limited. Finally in the case of degenerative senile trembling its action is less effective. Tolerance to tiapride seemed to be excellent even at high dose.
作者对37例异常运动患者和20例源于焦虑抑郁的震颤患者试用了硫必利。硫必利的最佳适应证是由抗精神病药物引起的舌颊面部运动障碍以及因酗酒加重的老年震颤。另一方面,其抗焦虑和抗震颤特性较为有限。最后,在退行性老年震颤的情况下,其作用效果较差。即使在高剂量时,对硫必利的耐受性似乎也很好。