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重症皮肤毛霉病管理中的挑战:一例糖尿病控制不佳且伴有多种微生物感染的快速进展病例

Challenges in the management of severe cutaneous mucormycosis: A case of rapid progression in uncontrolled diabetes mellitus with polymicrobial implications.

作者信息

Harrar Sara, Mimouni Nidae, Kharchi Rabie, Abkari Imad, El Hakkouni Awatif

机构信息

Parasitology-Mycology Laboratory Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakech, 40000, Morocco.

Traumatology-Orthopedy B Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakech, 40000, Morocco.

出版信息

Med Mycol Case Rep. 2024 Mar 8;44:100643. doi: 10.1016/j.mmcr.2024.100643. eCollection 2024 Jun.

Abstract

Mucormycosis, a rare but life-threatening fungal infection, poses significant challenges in clinical management, particularly in patients with uncontrolled diabetes mellitus. This case report presents the clinical journey of a 44-year-old woman who developed a rapidly progressing Mucorales infection following a domestic knife injury. Her condition, complicated by diabetic ketoacidosis and co-infection with , led to severe hand phlegm and sepsis. Despite aggressive intervention, the infection continued to advance, ultimately resulting in the patient's demise.

摘要

毛霉菌病是一种罕见但危及生命的真菌感染,在临床管理中带来重大挑战,尤其是在糖尿病控制不佳的患者中。本病例报告介绍了一名44岁女性的临床病程,她在遭受家用刀具损伤后发生了快速进展的毛霉目感染。她的病情因糖尿病酮症酸中毒和合并感染而复杂化,导致严重的手部蜂窝织炎和败血症。尽管进行了积极干预,但感染仍持续进展,最终导致患者死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8d6/10950793/41a686687248/gr1.jpg

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