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超越传统方法:增强由……引起的难治性猫孢子丝菌病的光动力疗法

Beyond conventional approaches: Enhancing photodynamic therapy for refractory feline sporotrichosis caused by .

作者信息

Mesquita Ramos Mariana Lucy, de Souza Rabello Vanessa Brito, Ribeiro da Silva Erica Aparecida Dos Santos, da Silva Lourenço Maria Cristina, Almeida-Paes Rodrigo, Frases Susana

机构信息

Laboratório de Biofísica de Fungos, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.

Laboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.

出版信息

Med Mycol Case Rep. 2024 Mar 6;44:100642. doi: 10.1016/j.mmcr.2024.100642. eCollection 2024 Jun.

Abstract

Male cat, 2 years old, with a refractory infection by Sporothrix brasiliensis, presents a single nodular lesion in the left auricular pavilion. To confirm the diagnosis, cytology, fungal culture, antifungal susceptibility test, molecular analysis, and, to aid in the differential diagnosis, bacterial culture, antibiogram, and histopathology of the lesion were performed. In the absence of therapeutic success with conventional antifungals, photodynamic therapy (PDT) was introduced, demonstrating a satisfactory response in the sixth treatment session.

摘要

雄性猫,2岁,患有巴西孢子丝菌难治性感染,左耳廓出现单个结节性病变。为确诊,进行了细胞学检查、真菌培养、抗真菌药敏试验、分子分析,并且为辅助鉴别诊断,还对病变进行了细菌培养、药敏试验和组织病理学检查。在常规抗真菌药物治疗未取得成功的情况下,采用了光动力疗法(PDT),在第六次治疗时显示出令人满意的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79f5/10955073/88c09574d993/gr1.jpg

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